| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Final Destination | $101,571 | -34.4% | 29 | - | $3,502 | $493,590 | 3 | Warner Bros. | false | false |
| 2 | 2 | Tarata | $81,984 | -46.2% | 32 | - | $2,562 | $294,319 | 2 | N/A | false | false |
| 3 | 3 | The Ugly Truth | $68,693 | -31.3% | 26 | -1 | $2,642 | $383,305 | 3 | Sony Pictures Releasing | false | false |
| 4 | - | The Uninvited | $59,864 | - | 21 | - | $2,850 | $59,864 | 1 | Paramount Pictures International | true | false |
| 5 | 4 | Tinker Bell and the Lost Treasure | $51,176 | -26.4% | 22 | - | $2,326 | $133,793 | 2 | Walt Disney Pictures | false | false |
| 6 | - | My Sister's Keeper | $47,106 | - | 12 | - | $3,925 | $53,370 | 1 | Warner Bros. | true | false |
| 7 | 5 | Aliens in the Attic | $40,187 | -20.4% | 28 | - | $1,435 | $467,832 | 5 | 20th Century Fox International | false | false |
| 8 | - | Death at a Funeral | $35,277 | - | 10 | - | $3,527 | $36,240 | 1 | N/A | true | false |
| 9 | - | 12 Rounds | $26,385 | - | 13 | - | $2,029 | $26,385 | 1 | 20th Century Fox International | true | false |
| 10 | 6 | The Taking of Pelham 123 | $23,385 | -3.4% | 17 | - | $1,375 | $349,767 | 5 | Sony Pictures Releasing | false | false |
| 11 | - | Grace Is Gone | $17,071 | - | 10 | - | $1,707 | $17,071 | 1 | N/A | true | false |
| 12 | 18 | The Last House on the Left | $14,590 | +150.3% | 20 | - | $729 | $178,405 | 5 | Universal Pictures International (UPI) | false | false |
| 13 | 8 | Shorts | $8,604 | -39.5% | 27 | - | $318 | $268,735 | 7 | Warner Bros. | false | false |
| 14 | 7 | Mama's Boy | $8,426 | -63.7% | 10 | - | $842 | $40,584 | 2 | N/A | false | false |
| 15 | 9 | Diary of a Nymphomaniac | $5,259 | -60.4% | 10 | - | $525 | $65,011 | 3 | N/A | false | false |
| 16 | 13 | Year One | $4,298 | -54.1% | 3 | -3 | $1,432 | $246,213 | 7 | Sony Pictures Releasing | false | false |
| 17 | 22 | G-Force | $3,944 | +0.8% | 42 | - | $93 | $1,863,533 | 9 | Walt Disney Pictures | false | false |
| 18 | - | Balls of Fury | $3,801 | - | 14 | - | $271 | $30,743 | 4 | N/A | false | false |
| 19 | 10 | The Hangover | $3,564 | -72.1% | 28 | - | $127 | $423,433 | 6 | Warner Bros. | false | false |
| 20 | 24 | Igor | $3,437 | +90.8% | 20 | - | $171 | $61,578 | 7 | N/A | false | false |
| 21 | 20 | The Proposal | $3,069 | -23.8% | 30 | - | $102 | $617,329 | 10 | Walt Disney Pictures | false | false |
| 22 | 30 | The Killing Gene | $2,392 | +645.2% | 15 | - | $159 | $77,774 | 6 | N/A | false | false |
| 23 | 11 | Orphan | $2,387 | -77.4% | 21 | - | $113 | $626,784 | 8 | Warner Bros. | false | false |
| 24 | 12 | Push | $2,355 | -75.7% | 25 | - | $94 | $97,519 | 5 | N/A | false | false |
| 25 | 16 | Apartment 1303 | $1,962 | -73.2% | 8 | - | $245 | $66,573 | 4 | N/A | false | false |
| 26 | - | Happy-Go-Lucky | $1,918 | - | 5 | - | $383 | $67,803 | 10 | N/A | false | false |
| 27 | 25 | The Haunting in Connecticut | $1,583 | +7.4% | 25 | - | $63 | $468,185 | 9 | N/A | false | false |
| 28 | 15 | The Air I Breathe | $1,133 | -86.1% | 15 | - | $75 | $44,677 | 3 | N/A | false | false |
| 29 | 23 | The Visitor | $1,089 | -67.1% | 6 | - | $181 | $18,268 | 4 | N/A | false | false |
| 30 | 14 | Mancora | $665 | -92.8% | 16 | - | $41 | $153,003 | 4 | N/A | false | false |
| 31 | - | The Wrestler | $272 | - | 14 | - | $19 | $55,422 | 19 | N/A | false | false |
| 32 | 27 | Rogue | $168 | -85% | 15 | - | $11 | $57,630 | 6 | N/A | false | false |
| 33 | - | Ice Age: Dawn of the Dinosaurs | $122 | - | 75 | - | $1 | $4,812,886 | 13 | 20th Century Fox International | false | false |
