| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | District 9 | $20,138 | - | 7 | - | $2,876 | $20,138 | 1 | Sony Pictures Releasing | true | false |
| 2 | - | Write Me - Postcards to Copacabana | $15,925 | - | 7 | - | $2,275 | $15,925 | 1 | N/A | true | false |
| 3 | 2 | G-Force | $11,123 | +3.4% | 2 | -2 | $5,561 | $225,846 | 10 | Walt Disney Pictures | false | false |
| 4 | 1 | The Ugly Truth | $10,785 | -36.7% | 4 | -1 | $2,696 | $33,743 | 2 | Sony Pictures Releasing | false | false |
| 5 | - | My Sister's Keeper | $6,918 | - | 3 | - | $2,306 | $6,918 | 1 | Warner Bros. | true | false |
| 6 | 5 | Aliens in the Attic | $6,412 | -2.6% | 3 | -1 | $2,137 | $73,488 | 6 | 20th Century Fox International | false | false |
| 7 | 3 | The Taking of Pelham 123 | $5,583 | -36.6% | 4 | -2 | $1,395 | $57,055 | 4 | Sony Pictures Releasing | false | false |
| 8 | 6 | The Accidental Husband | $5,515 | -10.8% | 3 | - | $1,838 | $27,429 | 3 | Walt Disney Pictures | false | false |
| 9 | 4 | Knowing | $5,379 | -26.4% | 3 | - | $1,793 | $28,193 | 3 | - | false | false |
| 10 | 9 | Southern District | $2,392 | -26% | 2 | - | $1,196 | $99,922 | 7 | N/A | false | false |
| 11 | 11 | Sex Drive | $1,989 | -22.7% | 1 | - | $1,989 | $26,199 | 5 | - | false | false |
| 12 | - | Flyboys 2008 Re-release | $1,826 | - | 2 | - | $913 | $1,826 | 1 | - | true | false |
| 13 | 7 | Ice Age: Dawn of the Dinosaurs | $1,146 | -77.5% | 2 | -1 | $573 | $853,027 | 14 | 20th Century Fox International | false | false |
| 14 | 12 | Duplicity | $933 | -62.3% | 2 | -2 | $466 | $9,934 | 3 | United International Pictures | false | false |
| 15 | 13 | The Ugly Duckling and Me! | $544 | -75.4% | 2 | -2 | $272 | $7,194 | 3 | - | false | false |
| 16 | 17 | The Hangover | $541 | -44.6% | 1 | - | $541 | $52,777 | 6 | Warner Bros. | false | false |
| 17 | 16 | Imagine That | $285 | -77.4% | 1 | -3 | $285 | $18,444 | 4 | United International Pictures | false | false |
