| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Ugly Truth | $243,288 | - | 30 | - | $8,109 | $8,110 | 1 | Sony Pictures Releasing | true | false |
| 2 | 1 | Surrogates | $161,402 | -51.3% | 30 | - | $5,380 | $52,483 | 2 | Walt Disney Pictures | false | false |
| 3 | - | Whiteout | $98,939 | - | 26 | - | $3,805 | $98,939 | 1 | Warner Bros. | true | false |
| 4 | 3 | G.I. Joe: The Rise of Cobra | $25,698 | +32.2% | 7 | +5 | $3,671 | $2,106,241 | 10 | United International Pictures | false | false |
| 5 | - | Inglourious Basterds | $21,858 | - | 24 | - | $910 | $21,858 | - | United International Pictures | - | false |
| 6 | 5 | Public Enemies | $19,891 | +172.5% | 7 | +3 | $2,841 | $703,427 | 12 | United International Pictures | false | false |
| 7 | 2 | G-Force | $11,815 | -82.3% | 11 | -19 | $1,074 | $1,183,643 | 4 | Walt Disney Pictures | false | false |
| 8 | 4 | Star Trek | $4,087 | -71.1% | 2 | -4 | $2,043 | $1,048,996 | 18 | United International Pictures | false | false |
| 9 | 8 | The Proposal | $1,696 | -16.1% | 1 | -1 | $1,696 | $818,998 | 8 | Walt Disney Pictures | false | false |
| 10 | 6 | Harry Potter and the Half-Blood Prince | $770 | -72.3% | 1 | - | $770 | $3,709,805 | 13 | Warner Bros. | false | false |
| 11 | 7 | The Hangover | $598 | -76.8% | 1 | -2 | $598 | $249,579 | 7 | Warner Bros. | false | false |
