| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | G-Force | $40,724 | -6.8% | 11 | -1 | $3,702 | $186,678 | 3 | Universal Pictures International (UPI) | false | false |
| 2 | 2 | The Ugly Truth | $16,706 | -24.1% | 4 | -3 | $4,176 | $158,200 | 4 | Sony Pictures Releasing | false | false |
| 3 | 3 | Orphan | $13,375 | -31.7% | 7 | - | $1,910 | $47,374 | 2 | - | false | false |
| 4 | - | Jennifer's Body | $12,912 | - | 5 | - | $2,582 | $12,912 | 1 | Universal Pictures International (UPI) | true | false |
| 5 | - | Fame | $12,908 | - | 6 | - | $2,151 | $13,030 | 1 | ACME | true | false |
| 6 | - | 9 | $11,409 | - | 3 | - | $3,803 | $11,409 | 1 | Universal Pictures International (UPI) | true | false |
| 7 | 4 | The Final Destination | $8,832 | -32.1% | 6 | - | $1,472 | $196,989 | 5 | - | false | false |
| 8 | 6 | Up | $7,975 | -16% | 8 | -2 | $996 | $410,360 | 7 | Universal Pictures International (UPI) | false | false |
| 9 | 5 | Pandorum | $6,183 | -43.6% | 4 | - | $1,545 | $23,444 | 2 | ACME | false | false |
| 10 | 7 | Inglourious Basterds | $4,375 | -45.7% | 4 | -2 | $1,093 | $162,287 | 6 | Universal Pictures International (UPI) | false | false |
| 11 | 8 | High Security Vacation | $2,186 | -60.5% | 3 | -1 | $728 | $64,636 | 5 | ACME | false | false |
| 12 | - | Two Lovers | $2,119 | - | 1 | - | $2,119 | $2,119 | 1 | ACME | true | false |
| 13 | 9 | Vortex | $1,510 | -46.5% | 3 | - | $503 | $36,709 | 17 | N/A | false | false |
| 14 | 13 | Diary of a Nymphomaniac | $1,204 | +27.7% | 1 | -1 | $1,204 | $39,578 | 9 | ACME | false | false |
| 15 | 11 | Whatever Works | $1,195 | -41.2% | 1 | - | $1,195 | $7,244 | 3 | ACME | false | false |
| 16 | - | Mid-August Lunch | $1,009 | - | 1 | - | $1,009 | $4,599 | 1 | N/A | true | false |
| 17 | 10 | Ice Age: Dawn of the Dinosaurs | $433 | -83.1% | 1 | -3 | $433 | $1,403,110 | 14 | Universal Pictures International (UPI) | false | false |
| 18 | 17 | G.I. Joe: The Rise of Cobra | $398 | +9.9% | 3 | - | $132 | $55,571 | 8 | Universal Pictures International (UPI) | false | false |
| 19 | 12 | My Sister's Keeper | $347 | -77.4% | 4 | - | $86 | $115,146 | 9 | - | false | false |
| 20 | 19 | District 9 | $267 | -2.9% | 2 | -5 | $133 | $96,566 | 8 | Sony Pictures Releasing | false | false |
