| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Secret in Their Eyes | $402,973 | -13.3% | 89 | - | $4,527 | $7,442,552 | 9 | Distribution Company | false | false |
| 2 | 2 | Cloudy with a Chance of Meatballs | $310,983 | -2.5% | 71 | +1 | $4,380 | $709,096 | 2 | Sony Pictures Releasing | false | false |
| 3 | 3 | The Final Destination | $158,674 | -7.2% | 69 | +6 | $2,299 | $1,475,204 | 4 | Distribution Company | false | false |
| 4 | 4 | The Widows of Thursdays | $120,926 | -16% | 80 | +4 | $1,511 | $1,666,951 | 5 | Alfa Films | false | false |
| 5 | - | My Life in Ruins | $118,702 | - | 40 | - | $2,967 | $147,098 | 1 | Distribution Company | true | false |
| 6 | 5 | Broken Embraces | $103,161 | -27.1% | 35 | - | $2,947 | $302,496 | 2 | Universal Pictures International (UPI) | false | false |
| 7 | 6 | District 9 | $75,848 | -19.9% | 45 | - | $1,685 | $398,812 | 3 | Sony Pictures Releasing | false | false |
| 8 | 7 | Orphan | $75,536 | -11.7% | 37 | - | $2,041 | $356,550 | 3 | Warner Bros. | false | false |
| 9 | 8 | A Matter of Principles | $63,278 | -6.8% | 36 | +1 | $1,757 | $288,664 | 3 | N/A | false | false |
| 10 | 9 | Inglourious Basterds | $58,173 | -10.7% | 56 | +4 | $1,038 | $1,054,938 | 6 | Universal Pictures International (UPI) | false | false |
| 11 | 11 | Julie & Julia | $38,871 | -17.1% | 40 | +5 | $971 | $386,551 | 4 | Sony Pictures Releasing | false | false |
| 12 | - | The Dolphin: Story of a Dreamer | $35,328 | - | 20 | - | $1,766 | $48,080 | 1 | 20th Century Fox International | true | false |
| 13 | 10 | Jennifer's Body | $26,708 | -49.1% | 26 | - | $1,027 | $105,606 | 2 | 20th Century Fox International | false | false |
| 14 | 12 | The Ugly Truth | $20,760 | -24.9% | 24 | -3 | $865 | $490,979 | 7 | Sony Pictures Releasing | false | false |
| 15 | - | The Meerkats | $19,802 | - | 34 | - | $582 | $25,948 | 1 | Alfa Films | true | false |
| 16 | 15 | Tinker Bell and the Lost Treasure | $18,392 | -15.3% | 48 | +1 | $383 | $516,990 | 6 | Walt Disney Pictures | false | false |
| 17 | 14 | The Time Traveler's Wife | $17,163 | -22.8% | 29 | -1 | $591 | $115,519 | 3 | Distribution Company | false | false |
| 18 | 16 | Shorts | $15,993 | +28.2% | 20 | - | $799 | $191,671 | 5 | Warner Bros. | false | false |
| 19 | 13 | Dad for a Day | $14,582 | -40.8% | 42 | -15 | $347 | $1,720,984 | 10 | Walt Disney Pictures | false | false |
| 20 | 23 | My Best Friend's Girl | $8,306 | +81.4% | 9 | +2 | $922 | $77,580 | 4 | Alfa Films | false | false |
| 21 | 18 | The Hangover | $7,113 | -26.8% | 10 | -17 | $711 | $849,696 | 9 | Warner Bros. | false | false |
| 22 | 20 | Cherry Blossoms | $6,973 | +0.6% | 5 | - | $1,394 | $49,026 | 4 | Alfa Films | false | false |
| 23 | 21 | Aliens in the Attic | $6,083 | -4.5% | 32 | +1 | $190 | $193,912 | 8 | 20th Century Fox International | false | false |
| 24 | - | Ashes of Time | $5,957 | - | 4 | - | $1,489 | $7,566 | 1 | Distribution Company | true | false |
| 25 | 19 | G-Force | $5,897 | -37.1% | 22 | -11 | $268 | $2,105,940 | 11 | Walt Disney Pictures | false | false |
| 26 | 24 | The Haunting in Connecticut | $5,836 | +28.7% | 11 | - | $530 | $199,125 | 8 | Alfa Films | false | false |
| 27 | 17 | Anita | $5,241 | -52% | 33 | -8 | $158 | $396,381 | 7 | Distribution Company | false | false |
| 28 | - | Nunca estuviste tan adorable | $3,780 | - | 5 | - | $756 | $5,004 | 1 | Primer Plano Film Group | true | false |
| 29 | 28 | Coco Before Chanel | $3,763 | +39.8% | 17 | +7 | $221 | $211,437 | 7 | Warner Bros. | false | false |
| 30 | 27 | Traitor | $2,537 | -11.8% | 3 | -5 | $845 | $64,347 | 5 | Distribution Company | false | false |
| 31 | 26 | Ice Age: Dawn of the Dinosaurs | $2,170 | -37.3% | 7 | -5 | $310 | $8,068,395 | 15 | 20th Century Fox International | false | false |
| 32 | 22 | My Bloody Valentine | $1,920 | -63.2% | 12 | -4 | $160 | $573,487 | 6 | Alfa Films | false | false |
| 33 | 30 | Homero Manzi, un poeta en la tormenta | $1,869 | -21.8% | 5 | - | $373 | $13,376 | 3 | Primer Plano Film Group | false | false |
| 34 | 31 | Hannah Montana: The Movie | $1,057 | -54% | 5 | -2 | $211 | $457,944 | 9 | Walt Disney Pictures | false | false |
| 35 | 35 | Tierra sublevada: Oro impuro | $969 | +81.8% | 3 | +2 | $323 | $13,998 | 5 | Primer Plano Film Group | false | false |
| 36 | 29 | Street Fighter: The Legend of Chun-Li | $748 | -71.5% | 4 | -1 | $187 | $4,846 | 2 | Distribution Company | false | false |
| 37 | 25 | The Wave | $746 | -79.9% | 3 | -2 | $248 | $180,238 | 8 | Impacto Cine | false | false |
| 38 | 39 | Mentiras piadosas | $661 | +230.5% | 3 | +1 | $220 | $20,176 | 8 | N/A | false | false |
| 39 | 48 | The Age of Stupid | $547 | +1,557.6% | 1 | - | $547 | $3,072 | 3 | N/A | false | false |
| 40 | 33 | Drag Me to Hell | $472 | -24.6% | 3 | -2 | $157 | $449,235 | 9 | Universal Pictures International (UPI) | false | false |
| 41 | 32 | Giovanna's Father 2009 Re-release | $467 | -72.1% | 3 | -1 | $155 | $9,129 | 3 | Primer Plano Film Group | false | false |
| 42 | 36 | The Secret of the Grain | $370 | -21.1% | 1 | -1 | $370 | $83,442 | 11 | N/A | false | false |
| 43 | 45 | Transformers: Revenge of the Fallen | $171 | +180.3% | 2 | +1 | $85 | $2,491,004 | 16 | Paramount Pictures International | false | false |
| 44 | 42 | Harry Potter and the Half-Blood Prince | $148 | +54.2% | 1 | - | $148 | $4,461,626 | 12 | Warner Bros. | false | false |
| 45 | 37 | El hombre que corría tras el viento | $145 | -66.8% | 1 | -1 | $145 | $36,014 | 6 | Primer Plano Film Group | false | false |
| 46 | 41 | Wild Blood | $141 | - | 1 | - | $141 | $21,262 | 6 | Pachamama Cine | false | false |
| 47 | 34 | G.I. Joe: The Rise of Cobra | $130 | -78.3% | 1 | -3 | $130 | $451,933 | 10 | Paramount Pictures International | false | false |
| 48 | 40 | The Dress | $46 | -70.1% | 1 | -3 | $46 | $5,948 | 4 | Primer Plano Film Group | false | false |
| 49 | 43 | Breath 2009 Re-release | $31 | -57.5% | 1 | - | $31 | $20,537 | 11 | Distribution Company | false | false |
