| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Couples Retreat | $2,683,905 | - | 217 | - | $12,368 | $2,733,640 | 1 | Universal Pictures International (UPI) | true | false |
| 2 | 1 | Up | $1,896,703 | -27.9% | 355 | -55 | $5,342 | $22,635,060 | 6 | Buena Vista International | false | false |
| 3 | 2 | Mao's Last Dancer | $1,839,749 | -22.7% | 267 | +1 | $6,890 | $5,765,269 | 2 | Roadshow Films | false | false |
| 4 | - | Julie & Julia | $1,336,860 | - | 285 | - | $4,690 | $1,796,190 | 1 | Sony Pictures Releasing | true | false |
| 5 | 3 | G-Force | $1,299,844 | -21.6% | 327 | -23 | $3,975 | $8,042,411 | 4 | Walt Disney Pictures | false | false |
| 6 | 5 | Surrogates | $517,234 | -47.6% | 181 | -25 | $2,857 | $4,104,329 | 3 | Walt Disney Pictures | false | false |
| 7 | - | Whip It | $479,586 | - | 152 | - | $3,155 | $479,586 | 1 | Roadshow Films | true | false |
| 8 | 4 | Fame | $457,867 | -54.1% | 288 | - | $1,589 | $4,480,798 | 3 | Icon Film Distribution | false | false |
| 9 | 6 | 500 Days of Summer | $230,190 | -57.2% | 153 | -69 | $1,504 | $3,961,438 | 4 | 20th Century Fox International | false | false |
| 10 | 8 | Inglourious Basterds | $184,984 | -43.4% | 107 | -55 | $1,728 | $11,979,947 | 8 | Universal Pictures International (UPI) | false | false |
| 11 | 7 | Funny People | $164,475 | -65.3% | 115 | -87 | $1,430 | $5,693,389 | 5 | Universal Pictures International (UPI) | false | false |
| 12 | - | Astro Boy | $162,232 | - | 171 | - | $948 | $162,232 | - | Hoyts Distribution | - | false |
| 13 | 9 | Aliens in the Attic | $148,611 | -51.8% | 129 | -61 | $1,152 | $3,478,005 | 6 | 20th Century Fox International | false | false |
| 14 | - | Moon | $130,576 | - | 13 | - | $10,044 | $130,576 | 1 | Sony Pictures Releasing | true | false |
| 15 | 11 | Shorts | $111,978 | -42.9% | 109 | -41 | $1,027 | $929,595 | 4 | Warner Bros. | false | false |
| 16 | 12 | Charlie & Boots | $85,695 | -48.3% | 90 | -32 | $952 | $3,181,076 | 6 | Paramount Pictures International | false | false |
| 17 | 14 | District 9 | $54,467 | -41% | 43 | -32 | $1,266 | $7,469,104 | 9 | Sony Pictures Releasing | false | false |
| 18 | 13 | The Young Victoria | $54,179 | -52% | 67 | -18 | $808 | $3,767,151 | 7 | Roadshow Films | false | false |
| 19 | - | Dinosaurs Alive | $44,130 | - | 1 | - | $44,130 | $242,030 | 7 | IMAX | false | false |
| 20 | 16 | Looking for Eric | $44,121 | -31.5% | 22 | - | $2,005 | $315,505 | 3 | Icon Film Distribution | false | false |
| 21 | - | Whatever Works | $20,932 | - | 27 | - | $775 | $20,932 | - | Hopscotch Films | - | false |
| 22 | - | Kiss of Life 2009 Re-release | $5,483 | - | 1 | - | $5,483 | $5,483 | 1 | Roadshow Films | true | false |
| 23 | - | The Private Lives of Pippa Lee | $1,632 | - | 1 | - | $1,632 | $1,632 | 1 | Icon Film Distribution | true | false |
