| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 2 | Surrogates | $123,172 | -15.2% | 66 | - | $1,866 | $344,807 | 2 | Walt Disney Pictures | false | false |
| 2 | - | Drag Me to Hell | $80,032 | - | 38 | - | $2,106 | $80,032 | 1 | United International Pictures | true | false |
| 3 | 4 | The Final Destination | $62,150 | -25.8% | 45 | -3 | $1,381 | $1,040,569 | 5 | Cine Colombia | false | false |
| 4 | 3 | District 9 | $60,573 | -28.1% | 40 | - | $1,514 | $342,822 | 3 | Sony Pictures Releasing | false | false |
| 5 | 5 | The Taking of Pelham 123 | $52,593 | -27.3% | 51 | -5 | $1,031 | $656,979 | 5 | Sony Pictures Releasing | false | false |
| 6 | 6 | The Ugly Truth | $39,268 | -34.7% | 39 | -1 | $1,006 | $752,800 | 7 | Sony Pictures Releasing | false | false |
| 7 | - | The Dolphin: Story of a Dreamer | $35,288 | - | 31 | - | $1,138 | $35,288 | 1 | 20th Century Fox International | true | false |
| 8 | - | Julie & Julia | $34,640 | - | 11 | - | $3,149 | $34,640 | 1 | Sony Pictures Releasing | true | false |
| 9 | - | Coco Before Chanel | $24,594 | - | 8 | - | $3,074 | $24,892 | 1 | Warner Bros. | true | false |
| 10 | 7 | Aliens in the Attic | $17,521 | -39.4% | 37 | -7 | $473 | $332,556 | 5 | 20th Century Fox International | false | false |
| 11 | 11 | The Uninvited | $16,479 | +38.2% | 21 | +5 | $784 | $184,702 | 6 | United International Pictures | false | false |
| 12 | 1 | Cloudy with a Chance of Meatballs | $15,462 | -96.7% | 1 | -81 | $15,462 | $41,775 | 2 | Sony Pictures Releasing | false | false |
| 13 | 10 | Shorts | $7,166 | -40.5% | 27 | -13 | $265 | $334,503 | 7 | Warner Bros. | false | false |
| 14 | 15 | Orphan | $6,690 | -20.1% | 16 | -4 | $418 | $565,037 | 8 | Warner Bros. | false | false |
| 15 | 8 | The Hangover | $6,113 | -51.4% | 9 | -11 | $679 | $938,952 | 9 | Warner Bros. | false | false |
| 16 | 9 | The Accidental Husband | $5,467 | -55.2% | 11 | -13 | $497 | $186,978 | 5 | Walt Disney Pictures | false | false |
| 17 | 12 | The Reader | $4,956 | -57.3% | 4 | -5 | $1,239 | $110,833 | 5 | Cineplex | false | false |
| 18 | 13 | G-Force | $4,294 | -56.5% | 13 | -15 | $330 | $2,641,549 | 11 | Walt Disney Pictures | false | false |
| 19 | 14 | Blackout 2009 Re-release | $3,056 | -63.6% | 10 | -2 | $305 | $16,956 | 2 | Cine Colombia | false | false |
| 20 | 17 | Public Enemies | $1,194 | -75.8% | 3 | -4 | $398 | $504,839 | 8 | United International Pictures | false | false |
| 21 | 16 | Venezzia | $1,190 | -81.6% | 7 | -20 | $170 | $62,874 | 3 | United International Pictures | false | false |
| 22 | 20 | Elegy | $803 | +3.7% | 3 | - | $267 | $106,613 | 14 | Cine Colombia | false | false |
| 23 | 18 | In Bruges | $778 | -67.3% | 1 | -1 | $778 | $33,156 | 6 | Cine Colombia | false | false |
