| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Cloudy with a Chance of Meatballs | $74,492 | -8.7% | 12 | -26 | $6,207 | $457,142 | 4 | Sony Pictures Releasing | false | false |
| 2 | - | Land of the Lost | $50,282 | - | 23 | - | $2,186 | $164,871 | 2 | United International Pictures | false | false |
| 3 | 2 | Surrogates | $48,843 | -26.9% | 24 | - | $2,035 | $146,989 | 2 | Walt Disney Pictures | false | false |
| 4 | - | The Dolphin: Story of a Dreamer | $47,486 | - | 14 | - | $3,391 | $47,486 | 1 | 20th Century Fox International | true | false |
| 5 | 3 | Shorts | $29,329 | -29.7% | 23 | - | $1,275 | $149,479 | 3 | - | false | false |
| 6 | - | Orphan | $22,464 | - | 9 | - | $2,496 | $22,464 | 1 | - | true | false |
| 7 | 5 | Ghosts of Girlfriends Past | $18,442 | -2.3% | 9 | - | $2,049 | $49,224 | 2 | - | false | false |
| 8 | 11 | Tinker Bell and the Lost Treasure | $13,354 | +254.9% | 14 | +3 | $953 | $161,135 | 6 | Walt Disney Pictures | false | false |
| 9 | 8 | Julie & Julia | $12,309 | -17.8% | 14 | - | $879 | $33,758 | 2 | Sony Pictures Releasing | false | false |
| 10 | 7 | My Sister's Keeper | $12,240 | -19.6% | 9 | - | $1,360 | $35,154 | 2 | - | false | false |
| 11 | 4 | The Ugly Truth | $9,795 | -55% | 15 | -4 | $653 | $272,922 | 5 | Sony Pictures Releasing | false | false |
| 12 | 9 | Aliens in the Attic | $6,305 | -44.7% | 14 | - | $450 | $189,129 | 5 | 20th Century Fox International | false | false |
| 13 | 6 | Year One | $5,986 | -61% | 12 | -2 | $498 | $73,112 | 3 | Sony Pictures Releasing | false | false |
| 14 | 12 | The Hangover | $4,278 | +227.1% | 5 | +2 | $855 | $194,589 | 8 | - | false | false |
| 15 | - | The Last House on the Left | $3,882 | - | 15 | - | $258 | $106,472 | 4 | United International Pictures | false | false |
| 16 | 15 | The Taking of Pelham 123 | $176 | -67.3% | 1 | -1 | $176 | $163,788 | 7 | Sony Pictures Releasing | false | false |
