| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | This Is It | $17,469 | -21.1% | 6 | - | $2,911 | $43,756 | 2 | Sony Pictures Releasing | false | false |
| 2 | - | Sorority Row | $14,761 | - | 5 | - | $2,952 | $14,761 | 1 | - | true | false |
| 3 | 2 | Inglourious Basterds | $11,858 | -19.8% | 8 | - | $1,482 | $120,354 | 4 | United International Pictures | false | false |
| 4 | 4 | Surrogates | $11,181 | -11.4% | 6 | - | $1,863 | $107,483 | 5 | Walt Disney Pictures | false | false |
| 5 | 6 | The Ugly Truth | $10,796 | +1.6% | 6 | - | $1,799 | $185,901 | 7 | Sony Pictures Releasing | false | false |
| 6 | 3 | Halloween II | $10,028 | -28.1% | 5 | - | $2,005 | $26,512 | 2 | N/A | false | false |
| 7 | 12 | Orphan | $9,915 | +160.4% | 5 | +3 | $1,983 | $99,655 | 6 | Warner Bros. | false | false |
| 8 | 5 | Management | $8,972 | -24.8% | 3 | - | $2,990 | $22,531 | 2 | N/A | false | false |
| 9 | 7 | Arn: The Knight Templar | $8,315 | -13.6% | 5 | - | $1,663 | $33,687 | 3 | - | false | false |
| 10 | 8 | The Final Destination | $8,125 | -11.5% | 4 | - | $2,031 | $229,005 | 8 | Warner Bros. | false | false |
| 11 | 9 | Funny People | $6,398 | -24.2% | 5 | - | $1,279 | $30,580 | 3 | United International Pictures | false | false |
| 12 | - | Dance Flick | $4,073 | - | 5 | - | $814 | $4,073 | 1 | United International Pictures | true | false |
| 13 | 10 | Whiteout | $3,877 | -33.2% | 5 | - | $775 | $23,986 | 3 | Warner Bros. | false | false |
| 14 | 11 | I Hate Valentine's Day | $2,985 | -29% | 1 | -2 | $2,985 | $27,718 | 4 | - | false | false |
| 15 | 13 | Jennifer's Body | $2,962 | -13.2% | 3 | - | $987 | $37,197 | 5 | 20th Century Fox International | false | false |
| 16 | 14 | Cloudy with a Chance of Meatballs | $1,498 | -20.7% | 3 | - | $499 | $41,733 | 8 | Sony Pictures Releasing | false | false |
| 17 | 15 | G.I. Joe: The Rise of Cobra | $990 | -43.3% | 3 | -3 | $330 | $101,978 | 7 | United International Pictures | false | false |
| 18 | 17 | Land of the Lost | $735 | -27.8% | 4 | +2 | $183 | $34,098 | 6 | United International Pictures | false | false |
| 19 | 18 | The Flight Before Christmas | $670 | -29.9% | 1 | -1 | $670 | $5,232 | 4 | - | false | false |
| 20 | - | Gamer | $245 | - | 1 | - | $245 | $72,864 | 8 | - | false | false |
| 21 | 20 | Blood: The Last Vampire | $178 | -23.9% | 2 | - | $89 | $5,723 | 4 | N/A | false | false |
| 22 | 21 | The Other Man | $86 | -23.9% | 1 | - | $86 | $21,289 | 6 | N/A | false | false |
| 23 | 19 | Imagine That | $66 | -79.6% | 1 | -1 | $66 | $64,478 | 14 | United International Pictures | false | false |
