| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 2 | Cloudy with a Chance of Meatballs | $40,791 | +9.7% | 9 | +1 | $4,532 | $263,058 | 3 | Sony Pictures Releasing | false | false |
| 2 | 1 | This Is It | $39,785 | +0.3% | 5 | - | $7,957 | $152,753 | 2 | Sony Pictures Releasing | false | false |
| 3 | - | The Time Traveler's Wife | $25,086 | - | 5 | - | $5,017 | $29,713 | 1 | - | true | false |
| 4 | 3 | Saw VI | $13,963 | -54.7% | 7 | - | $1,994 | $57,897 | 2 | ACME | false | false |
| 5 | 4 | OceanWorld | $10,071 | -12.3% | 4 | +1 | $2,517 | $193,817 | 5 | ACME | false | false |
| 6 | - | The Hurt Locker | $5,493 | - | 2 | - | $2,746 | $5,493 | 1 | ACME | true | false |
| 7 | 5 | Gamer | $4,927 | -31.2% | 5 | -1 | $985 | $44,095 | 3 | ACME | false | false |
| 8 | 8 | G-Force | $4,759 | +11.8% | 6 | -1 | $793 | $305,446 | 8 | Universal Pictures International (UPI) | false | false |
| 9 | 6 | Low Lights | $4,082 | -36.1% | 4 | - | $1,020 | $42,071 | 3 | ACME | false | false |
| 10 | 7 | Whiteout | $3,160 | -36.1% | 6 | -1 | $526 | $82,326 | 4 | - | false | false |
| 11 | 10 | Broken Embraces | $2,286 | -27.2% | 3 | - | $762 | $39,088 | 4 | ACME | false | false |
| 12 | - | The World is Big and Salvation Lurks Around the Corner | $2,260 | - | 1 | - | $2,260 | $2,260 | 2 | N/A | false | false |
| 13 | 12 | Inglourious Basterds | $1,705 | +56.6% | 1 | - | $1,705 | $185,220 | 11 | Universal Pictures International (UPI) | false | false |
| 14 | 9 | Surrogates | $1,663 | -47.1% | 4 | -2 | $415 | $102,052 | 5 | Universal Pictures International (UPI) | false | false |
| 15 | 11 | The Ugly Truth | $1,208 | -43.8% | 2 | - | $604 | $233,793 | 9 | Sony Pictures Releasing | false | false |
| 16 | 14 | The Final Destination | $1,169 | +86.7% | 3 | - | $389 | $224,820 | 10 | - | false | false |
| 17 | 16 | Orphan | $983 | +83.4% | 4 | - | $245 | $88,259 | 7 | - | false | false |
| 18 | 15 | Jennifer's Body | $712 | +32.3% | 2 | - | $356 | $50,036 | 6 | Universal Pictures International (UPI) | false | false |
| 19 | 18 | Whatever Works | $627 | +47.9% | 1 | - | $627 | $12,614 | 8 | ACME | false | false |
| 20 | - | I Always Wanted to Be a Gangster | $455 | - | 1 | - | $455 | $4,749 | 37 | Universal Pictures International (UPI) | false | false |
| 21 | 19 | Two Lovers | $349 | +26% | 1 | - | $349 | $6,812 | 6 | ACME | false | false |
| 22 | 21 | Vortex | $272 | +32% | 1 | -1 | $272 | $46,801 | 22 | N/A | false | false |
| 23 | 13 | 9 | $231 | -69.4% | 3 | - | $77 | $34,913 | 6 | Universal Pictures International (UPI) | false | false |
