| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | A Christmas Carol | $556,875 | - | 68 | - | $8,189 | $556,875 | 1 | Walt Disney Pictures | true | false |
| 2 | 1 | This Is It | $381,696 | -33.9% | 66 | -1 | $5,783 | $1,363,263 | 2 | Sony Pictures Releasing | false | false |
| 3 | 2 | Saw VI | $208,370 | -14.5% | 40 | - | $5,209 | $1,091,653 | 3 | Walt Disney Pictures | false | false |
| 4 | - | Drag Me to Hell | $177,336 | - | 41 | - | $4,325 | $186,388 | 1 | United International Pictures | true | false |
| 5 | 3 | Jennifer's Body | $154,769 | -26.7% | 44 | +1 | $3,517 | $526,778 | 2 | 20th Century Fox International | false | false |
| 6 | 4 | Cloudy with a Chance of Meatballs | $109,655 | -43.3% | 52 | -7 | $2,108 | $2,093,272 | 5 | Sony Pictures Releasing | false | false |
| 7 | 5 | Land of the Lost | $101,499 | -30.3% | 41 | +2 | $2,475 | $560,616 | 3 | United International Pictures | false | false |
| 8 | 13 | A Distant Place | $50,810 | +31.8% | 17 | +1 | $2,988 | $126,112 | 2 | N/A | false | false |
| 9 | 11 | Inglourious Basterds | $45,983 | +0.2% | 18 | -4 | $2,554 | $729,123 | 5 | United International Pictures | false | false |
| 10 | 6 | Whiteout | $39,959 | -66.5% | 21 | -14 | $1,902 | $511,051 | 3 | Warner Bros. | false | false |
| 11 | 10 | Venezzia | $39,167 | -23.5% | 21 | +1 | $1,865 | $1,096,276 | 7 | N/A | false | false |
| 12 | - | Be Kind Rewind | $34,566 | - | 9 | - | $3,840 | $34,566 | 1 | N/A | true | false |
| 13 | 8 | The Ugly Truth | $33,396 | -48.7% | 15 | -9 | $2,226 | $1,980,683 | 8 | Sony Pictures Releasing | false | false |
| 14 | 15 | Coco Before Chanel | $27,909 | +23% | 5 | -1 | $5,581 | $83,602 | 2 | Warner Bros. | false | false |
| 15 | 12 | The Uninvited | $22,749 | -44.6% | 16 | -2 | $1,421 | $452,853 | 4 | United International Pictures | false | false |
| 16 | 7 | District 9 | $22,656 | -68.9% | 13 | -15 | $1,742 | $608,653 | 4 | Sony Pictures Releasing | false | false |
| 17 | 14 | The Dolphin: Story of a Dreamer | $22,613 | -28.3% | 24 | -2 | $942 | $403,497 | 5 | 20th Century Fox International | false | false |
| 18 | 9 | Surrogates | $17,650 | -72.3% | 10 | -18 | $1,765 | $1,612,946 | 6 | Walt Disney Pictures | false | false |
| 19 | 20 | Broken Embraces | $12,305 | +162% | 7 | - | $1,757 | $151,453 | 4 | United International Pictures | false | false |
| 20 | 22 | Día naranja | $6,660 | +92.3% | 6 | +3 | $1,110 | $137,403 | 4 | N/A | false | false |
| 21 | 16 | 12 Rounds | $4,853 | -47.5% | 2 | -3 | $2,426 | $232,816 | 7 | 20th Century Fox International | false | false |
| 22 | 21 | Tinker Bell and the Lost Treasure | $1,820 | -54.3% | 9 | -7 | $202 | $438,225 | 10 | Walt Disney Pictures | false | false |
| 23 | 26 | School for Scoundrels 2009 Re-release | $1,728 | +72.6% | 3 | +1 | $576 | $337,657 | 10 | N/A | false | false |
| 24 | 25 | Aliens in the Attic | $1,338 | -39.6% | 6 | -2 | $223 | $1,919,023 | 11 | 20th Century Fox International | false | false |
| 25 | 24 | Orphan | $1,143 | -51% | 5 | +2 | $228 | $2,096,667 | 10 | Warner Bros. | false | false |
| 26 | 19 | Ghosts of Girlfriends Past | $540 | -89.3% | 1 | -1 | $540 | $968,933 | 10 | N/A | false | false |
| 27 | 23 | The Taking of Pelham 123 | $432 | -85.9% | 4 | -1 | $108 | $2,100,185 | 9 | Sony Pictures Releasing | false | false |
