| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Twilight Saga: New Moon | $1,400,168 | -46.9% | 91 | +2 | $15,386 | $4,338,579 | 2 | Belga Films | false | false |
| 2 | 2 | 2012 | $781,819 | -29% | 98 | - | $7,977 | $4,424,628 | 3 | Sony Pictures Releasing | false | false |
| 3 | 3 | A Christmas Carol | $307,302 | -4.6% | 59 | -7 | $5,208 | $736,573 | 2 | Walt Disney Pictures | false | false |
| 4 | 5 | Up | $179,672 | -1% | 92 | -28 | $1,952 | $6,896,154 | 8 | Walt Disney Pictures | false | false |
| 5 | 4 | Das Lied der Dinge | $159,224 | -19.3% | 31 | - | $5,136 | $3,276,743 | 8 | Kinepolis Film Distribution (KFD) | false | false |
| 6 | - | Paranormal Activity | $158,684 | - | 14 | - | $11,334 | $212,828 | 1 | Kinepolis Film Distribution (KFD) | true | false |
| 7 | 7 | The Barons | $123,225 | +0.5% | 12 | +2 | $10,268 | $669,349 | 4 | Cinéart | false | false |
| 8 | 6 | The Concert | $84,875 | -37% | 15 | +1 | $5,658 | $324,652 | 3 | Cinéart | false | false |
| 9 | 8 | The Box | $81,245 | -18.3% | 28 | - | $2,901 | $788,075 | 4 | Benelux Film Distributors | false | false |
| 10 | - | My Sister's Keeper | $80,859 | - | 20 | - | $4,042 | $106,450 | 1 | Warner Bros. | true | false |
| 11 | 11 | Love Happens | $46,445 | -40.6% | 16 | - | $2,902 | $148,441 | 2 | A-Film Distribution | false | false |
| 12 | 18 | Astro Boy | $45,850 | +67.3% | 24 | -12 | $1,910 | $469,780 | 5 | Belga Films | false | false |
| 13 | 10 | This Is It | $45,148 | -49.5% | 43 | -11 | $1,049 | $2,795,161 | 5 | Sony Pictures Releasing | false | false |
| 14 | 14 | The Informant! | $42,632 | -5.5% | 7 | - | $6,090 | $148,204 | 2 | Warner Bros. | false | false |
| 15 | 16 | Sinterklaas en de verdwenen pakjesboot | $40,953 | +11.6% | 16 | - | $2,559 | $235,943 | 5 | Kinepolis Film Distribution (KFD) | false | false |
| 16 | 12 | Trésor | $37,574 | -38.6% | 14 | - | $2,683 | $281,919 | 3 | Alternative Films | false | false |
| 17 | 13 | Little Nicholas | $37,120 | -19.3% | 30 | - | $1,237 | $1,800,588 | 9 | Cinéart | false | false |
| 18 | 15 | The Rebound | $28,001 | -26.5% | 22 | -2 | $1,272 | $300,328 | 3 | Paradiso Entertainment | false | false |
| 19 | 19 | The White Ribbon | $27,190 | +8.7% | 16 | - | $1,699 | $390,584 | 6 | Cinéart | false | false |
| 20 | - | Fish Tank | $26,484 | - | 8 | - | $3,310 | $38,592 | 1 | Cinéart | true | false |
| 21 | 23 | 500 Days of Summer | $18,221 | +14.2% | 8 | +1 | $2,277 | $207,674 | 4 | 20th Century Fox International | false | false |
| 22 | 17 | Surrogates | $17,598 | -38.6% | 15 | -9 | $1,173 | $1,205,833 | 6 | Walt Disney Pictures | false | false |
| 23 | 21 | Inglourious Basterds | $16,800 | -23.2% | 6 | -8 | $2,800 | $5,203,401 | 15 | Universal Pictures International (UPI) | false | false |
| 24 | - | Altiplano | $15,910 | - | 5 | - | $3,182 | $22,154 | 1 | N/A | true | false |
| 25 | 24 | G-Force | $14,947 | +22.6% | 8 | -4 | $1,868 | $3,074,239 | 18 | Walt Disney Pictures | false | false |
| 26 | 22 | Fame | $11,747 | -45% | 24 | -11 | $489 | $1,946,108 | 8 | Kinepolis Film Distribution (KFD) | false | false |
| 27 | 25 | Lilly the Witch: The Dragon and the Magic Book | $11,207 | +5.9% | 9 | -1 | $1,245 | $191,711 | 41 | Kinepolis Film Distribution (KFD) | false | false |
| 28 | 20 | Cirque du Freak: The Vampire's Assistant | $9,297 | -60.7% | 15 | -11 | $619 | $513,855 | 4 | Universal Pictures International (UPI) | false | false |
| 29 | 27 | Departures | $7,609 | -12.4% | 6 | - | $1,268 | $47,302 | 4 | N/A | false | false |
| 30 | 28 | Wild Grass | $7,001 | -16.6% | 8 | +3 | $875 | $51,315 | 4 | N/A | false | false |
| 31 | 26 | Micmacs | $6,512 | -34.5% | 13 | -11 | $500 | $400,517 | 5 | Cinéart | false | false |
| 32 | - | Simon Konianski | $5,814 | - | 8 | - | $726 | $6,296 | 1 | N/A | true | false |
| 33 | 34 | Jennifer's Body | $5,353 | +5.4% | 13 | -6 | $411 | $578,583 | 6 | 20th Century Fox International | false | false |
| 34 | - | The Taking of Pelham 123 | $3,936 | - | 1 | - | $3,936 | $1,579,177 | 18 | Sony Pictures Releasing | false | false |
