| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Avatar | $793,521 | -6.5% | 110 | -8 | $7,213 | $5,503,659 | 4 | 20th Century Fox International | false | false |
| 2 | - | Tooth Fairy | $105,261 | - | 38 | - | $2,770 | $105,261 | 1 | 20th Century Fox International | true | false |
| 3 | 2 | Paranormal Activity | $74,946 | -21.8% | 33 | -4 | $2,271 | $511,247 | 3 | N/A | false | false |
| 4 | - | Surrogates | $61,914 | - | 31 | - | $1,997 | $62,512 | 1 | Walt Disney Pictures | true | false |
| 5 | 3 | The Princess and the Frog | $54,421 | -23% | 31 | -10 | $1,755 | $780,008 | 6 | Walt Disney Pictures | false | false |
| 6 | - | Did You Hear About the Morgans? | $36,648 | - | 27 | - | $1,357 | $36,648 | 1 | Sony Pictures Releasing | true | false |
| 7 | - | Cirque du Freak: The Vampire's Assistant | $34,795 | - | 27 | - | $1,288 | $34,795 | 1 | United International Pictures | true | false |
| 8 | 4 | Old Dogs | $34,358 | -46.2% | 25 | -5 | $1,374 | $253,393 | 3 | Walt Disney Pictures | false | false |
| 9 | 6 | 2012 | $13,695 | -69.8% | 9 | -21 | $1,521 | $4,094,023 | 9 | Sony Pictures Releasing | false | false |
| 10 | 5 | 9 | $10,354 | -78.6% | 19 | -7 | $544 | $82,770 | 2 | N/A | false | false |
| 11 | 7 | Zombieland | $6,248 | -82.9% | 13 | -17 | $480 | $70,932 | 2 | Sony Pictures Releasing | false | false |
| 12 | 9 | Happy-Go-Lucky | $6,228 | -34.1% | 3 | - | $2,076 | $55,901 | 5 | N/A | false | false |
| 13 | 8 | The Twilight Saga: New Moon | $3,911 | -87.5% | 6 | -18 | $651 | $2,472,725 | 7 | N/A | false | false |
| 14 | 11 | Planet 51 | $1,332 | -74.9% | 4 | -4 | $333 | $267,037 | 7 | N/A | false | false |
| 15 | 16 | I've Loved You So Long | $101 | -90.7% | 1 | - | $101 | $63,427 | 8 | Transeuropa | false | false |
