| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Avatar | $650,693 | -13.7% | 123 | -32 | $5,290 | $9,144,840 | 6 | 20th Century Fox International | false | false |
| 2 | - | Tooth Fairy | $199,632 | - | 55 | - | $3,629 | $199,632 | 1 | 20th Century Fox International | true | false |
| 3 | 2 | Sherlock Holmes | $181,229 | -35% | 90 | -8 | $2,013 | $1,192,022 | 3 | Warner Bros. | false | false |
| 4 | 3 | Old Dogs | $102,664 | -30% | 46 | - | $2,231 | $598,904 | 3 | Walt Disney Pictures | false | false |
| 5 | 4 | Alvin and the Chipmunks: The Squeakquel | $77,576 | -47% | 81 | -8 | $957 | $1,144,390 | 4 | 20th Century Fox International | false | false |
| 6 | 5 | Paranormal Activity | $69,303 | -42.6% | 64 | -7 | $1,082 | $1,095,762 | 4 | Cine Colombia | false | false |
| 7 | 6 | The Princess and the Frog | $62,601 | -45.9% | 99 | -5 | $632 | $1,650,458 | 5 | Walt Disney Pictures | false | false |
| 8 | - | Up in the Air | $52,310 | - | 18 | - | $2,906 | $52,310 | 1 | United International Pictures | true | false |
| 9 | 7 | Zombieland | $22,238 | -61.9% | 31 | -4 | $717 | $110,871 | 2 | Sony Pictures Releasing | false | false |
| 10 | 10 | Departures | $14,774 | +10% | 4 | - | $3,693 | $38,628 | 2 | Cine Colombia | false | false |
| 11 | 9 | The Soloist | $10,513 | -26.9% | 5 | -1 | $2,102 | $33,324 | 2 | United International Pictures | false | false |
| 12 | 8 | Astro Boy | $9,637 | -64.3% | 25 | -2 | $385 | $45,413 | 2 | Cine Colombia | false | false |
| 13 | 12 | Flame & Citron | $2,517 | -28.4% | 3 | -1 | $839 | $24,732 | 4 | Cineplex | false | false |
| 14 | 11 | The Stepfather | $1,427 | -61.4% | 3 | -3 | $475 | $81,200 | 7 | Sony Pictures Releasing | false | false |
| 15 | 14 | Inglourious Basterds | $740 | -58.5% | 1 | -2 | $740 | $423,089 | 13 | United International Pictures | false | false |
