| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Avatar | $9,730,555 | -11.6% | 710 | -20 | $13,705 | $123,630,656 | 6 | 20th Century Fox International | false | false |
| 2 | 2 | Invictus | $5,194,822 | -22.5% | 480 | +12 | $10,822 | $13,264,810 | 2 | Warner Bros. | false | false |
| 3 | - | Gainsbourg: A Heroic Life | $3,974,235 | - | 499 | - | $7,964 | $3,974,235 | 1 | Universal Pictures International (UPI) | true | false |
| 4 | - | The Book of Eli | $2,178,709 | - | 378 | - | $5,763 | $2,178,709 | 1 | Metropolitan Filmexport | true | false |
| 5 | - | Did You Hear About the Morgans? | $1,868,710 | - | 313 | - | $5,970 | $1,892,546 | 1 | Sony Pictures Releasing | true | false |
| 6 | - | A Serious Man | $1,254,376 | - | 133 | - | $9,431 | $1,254,376 | 1 | StudioCanal | true | false |
| 7 | 3 | A Spot of Bother | $1,151,016 | -42.4% | 335 | +1 | $3,435 | $3,538,122 | 2 | UGC Distribution | false | false |
| 8 | 4 | Alvin and the Chipmunks: The Squeakquel | $961,642 | -14.8% | 443 | -70 | $2,170 | $11,818,620 | 5 | 20th Century Fox International | false | false |
| 9 | 5 | The Whistler | $532,882 | -50.4% | 267 | - | $1,995 | $3,632,878 | 3 | Europa Filmes | false | false |
| 10 | 6 | Orphan | $513,152 | -47% | 228 | -61 | $2,250 | $5,422,996 | 4 | Warner Bros. | false | false |
| 11 | - | Accomplices | $429,624 | - | 116 | - | $3,703 | $429,624 | 1 | Pyramide Distribution | true | false |
| 12 | 7 | Bright Star | $380,146 | -44.5% | 137 | -2 | $2,774 | $2,264,871 | 3 | N/A | false | false |
| 13 | 8 | Mr. Nobody | $294,821 | -54% | 139 | -11 | $2,121 | $1,051,211 | 2 | Pathé | false | false |
| 14 | 12 | Arthur and the Revenge of Maltazard | $238,173 | -51.5% | 328 | -99 | $726 | $35,942,985 | 8 | Europa Filmes | false | false |
| 15 | 10 | Armored | $200,632 | -62.2% | 104 | - | $1,929 | $829,007 | 2 | Sony Pictures Releasing | false | false |
| 16 | 9 | Agora | $194,123 | -69.7% | 161 | -141 | $1,205 | $2,328,651 | 3 | N/A | false | false |
| 17 | - | The Barons | $191,079 | - | 130 | - | $1,469 | $191,079 | 1 | N/A | true | false |
| 18 | 11 | It's Complicated | $178,770 | -64.8% | 159 | -135 | $1,124 | $6,262,170 | 5 | Universal Pictures International (UPI) | false | false |
| 19 | - | City Island | $141,304 | - | 43 | - | $3,286 | $141,304 | 1 | N/A | true | false |
| 20 | 14 | 2012 | $22,979 | -53.4% | 32 | -16 | $718 | $44,025,035 | 11 | Sony Pictures Releasing | false | false |
