| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Avatar | $40,938 | -23.6% | 8 | -1 | $5,117 | $631,529 | 6 | 20th Century Fox International | false | false |
| 2 | - | Invictus | $19,985 | - | 8 | - | $2,498 | $21,350 | 1 | Warner Bros. | true | false |
| 3 | 2 | Sherlock Holmes | $18,686 | -48.8% | 7 | -3 | $2,669 | $97,776 | 2 | Warner Bros. | false | false |
| 4 | 3 | It's Complicated | $14,685 | -31.7% | 7 | - | $2,097 | $83,615 | 2 | United International Pictures | false | false |
| 5 | - | Up in the Air | $12,363 | - | 8 | - | $1,545 | $63,166 | 1 | Paramount Pictures International | true | false |
| 6 | - | Old Dogs | $12,096 | - | 5 | - | $2,419 | $12,096 | 1 | Walt Disney Pictures | true | false |
| 7 | - | The Girl with the Dragon Tattoo | $8,440 | - | 4 | - | $2,110 | $25,776 | 1 | N/A | true | false |
| 8 | 4 | Alvin and the Chipmunks: The Squeakquel | $7,398 | -45.5% | 5 | - | $1,479 | $97,626 | 4 | 20th Century Fox International | false | false |
| 9 | 5 | The Young Victoria | $5,119 | -41.5% | 4 | - | $1,279 | $21,852 | 2 | N/A | false | false |
| 10 | 6 | The Princess and the Frog | $3,363 | -56.7% | 5 | - | $672 | $52,902 | 3 | Walt Disney Pictures | false | false |
| 11 | 8 | Paranormal Activity | $3,192 | -46.5% | 3 | -1 | $1,064 | $48,198 | 4 | N/A | false | false |
| 12 | 7 | All About Steve | $903 | -86.5% | 2 | -2 | $451 | $51,829 | 3 | 20th Century Fox International | false | false |
| 13 | 9 | Zombieland | $857 | -69.9% | 3 | -2 | $285 | $20,879 | 3 | Sony Pictures Releasing | false | false |
| 14 | 13 | The Twilight Saga: New Moon | $764 | -28.3% | 3 | - | $254 | $170,686 | 8 | N/A | false | false |
| 15 | 12 | 2012 | $760 | -41.6% | 3 | +1 | $253 | $358,329 | 11 | Sony Pictures Releasing | false | false |
| 16 | 15 | Late Bloomers 2009 Re-release | $561 | -43.2% | 1 | - | $561 | $9,562 | 6 | N/A | false | false |
| 17 | 11 | My Life in Ruins | $470 | -69.2% | 1 | - | $470 | $45,259 | 5 | N/A | false | false |
| 18 | 10 | Jennifer's Body | $460 | -75.9% | 2 | -1 | $230 | $3,665 | 2 | 20th Century Fox International | false | false |
| 19 | 16 | A Thousand Years of Good Prayers | $446 | -14.2% | 1 | - | $446 | $1,325 | 2 | N/A | false | false |
