| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Zero 2 | $69,393 | - | 7 | - | $9,913 | $79,110 | 1 | N/A | true | false |
| 2 | 1 | Avatar | $64,914 | -7.7% | 11 | - | $5,901 | $960,219 | 6 | 20th Century Fox International | false | false |
| 3 | - | The Book of Eli | $22,303 | - | 6 | - | $3,717 | $22,303 | 1 | Sony Pictures Releasing | true | false |
| 4 | 2 | It's Complicated | $17,336 | -39.9% | 6 | - | $2,889 | $65,021 | 2 | Universal Pictures International (UPI) | false | false |
| 5 | 4 | Alvin and the Chipmunks: The Squeakquel | $13,858 | -30.9% | 10 | - | $1,385 | $294,042 | 5 | Universal Pictures International (UPI) | false | false |
| 6 | 3 | Sherlock Holmes | $13,021 | -43.2% | 7 | - | $1,860 | $230,570 | 4 | - | false | false |
| 7 | - | The Princess and the Frog | $7,768 | - | 8 | - | $971 | $7,768 | - | Universal Pictures International (UPI) | - | false |
| 8 | 5 | Ninja Assassin | $3,867 | -71.5% | 6 | - | $644 | $26,892 | 2 | - | false | false |
| 9 | 6 | The Imaginarium of Doctor Parnassus | $3,482 | -61.7% | 5 | - | $696 | $37,526 | 3 | ACME | false | false |
| 10 | - | Up in the Air | $3,334 | - | 5 | - | $666 | $3,334 | 1 | Universal Pictures International (UPI) | true | false |
| 11 | 7 | Daybreakers | $3,135 | -62% | 6 | - | $522 | $47,097 | 3 | ACME | false | false |
| 12 | 8 | The Box | $3,065 | -57.6% | 4 | - | $766 | $16,438 | 2 | ACME | false | false |
| 13 | 9 | Black Lightning | $3,008 | -47.6% | 5 | - | $601 | $69,206 | 4 | Universal Pictures International (UPI) | false | false |
| 14 | 12 | In the Loop | $696 | -41.9% | 1 | - | $696 | $2,494 | 2 | N/A | false | false |
| 15 | 11 | A Christmas Carol | $444 | -68.4% | 3 | -1 | $148 | $249,653 | 10 | Universal Pictures International (UPI) | false | false |
| 16 | 13 | Everybody's Fine | $364 | -65.1% | 2 | -1 | $182 | $49,735 | 6 | Universal Pictures International (UPI) | false | false |
| 17 | 17 | The World is Big and Salvation Lurks Around the Corner | $326 | -16.6% | 1 | - | $326 | $17,879 | 13 | N/A | false | false |
| 18 | 16 | Golden Door 2010 Re-release | $307 | -22.7% | 1 | - | $307 | $1,527 | 3 | N/A | false | false |
| 19 | 10 | Couples Retreat | $147 | -93.1% | 2 | -2 | $73 | $155,068 | 8 | Universal Pictures International (UPI) | false | false |
| 20 | - | Looking for Eric | $104 | - | 1 | - | $104 | $2,370 | 5 | N/A | false | false |
