| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Avatar | $437,459 | +2.5% | 94 | - | $4,653 | $4,873,013 | 6 | 20th Century Fox International | false | false |
| 2 | - | Did You Hear About the Morgans? | $243,428 | - | 61 | - | $3,990 | $243,464 | 1 | N/A | true | false |
| 3 | 2 | Sherlock Holmes | $112,678 | -23.3% | 67 | - | $1,681 | $1,240,780 | 4 | N/A | false | false |
| 4 | 3 | Couples Retreat | $78,459 | -19.1% | 60 | -2 | $1,307 | $1,798,931 | 7 | N/A | false | false |
| 5 | 5 | Planet 51 | $72,662 | -14.9% | 53 | - | $1,370 | $516,539 | 3 | N/A | false | false |
| 6 | 4 | Alvin and the Chipmunks: The Squeakquel | $68,661 | -20.1% | 69 | -2 | $995 | $1,667,010 | 5 | N/A | false | false |
| 7 | 6 | The Rebound | $46,407 | -31.7% | 38 | -2 | $1,221 | $556,285 | 4 | N/A | false | false |
| 8 | 7 | Invictus | $42,910 | -24.9% | 44 | -3 | $975 | $1,371,412 | 7 | N/A | false | false |
| 9 | 8 | Brothers | $36,780 | -34% | 21 | - | $1,751 | $119,162 | 2 | N/A | false | false |
| 10 | 9 | 2012 | $36,459 | -32.6% | 36 | -11 | $1,012 | $2,266,300 | 8 | N/A | false | false |
| 11 | - | Skin | $25,593 | - | 11 | - | $2,326 | $25,593 | 1 | N/A | true | false |
| 12 | 10 | A Perfect Getaway | $25,361 | -31.5% | 25 | - | $1,014 | $149,942 | 3 | N/A | false | false |
| 13 | - | Amelia | $19,799 | - | 15 | - | $1,319 | $19,799 | 1 | N/A | true | false |
| 14 | 12 | Old Dogs | $15,803 | -22.2% | 19 | -5 | $831 | $1,452,095 | 9 | N/A | false | false |
| 15 | 13 | Paranormal Activity | $14,500 | -24.8% | 14 | -1 | $1,035 | $296,600 | 7 | N/A | false | false |
| 16 | 15 | Julie & Julia | $14,127 | +5.5% | 11 | -1 | $1,284 | $470,913 | 11 | N/A | false | false |
| 17 | 14 | The Stepfather | $9,742 | -29.5% | 18 | -1 | $541 | $166,488 | 4 | N/A | false | false |
| 18 | 17 | The September Issue | $4,636 | -32.4% | 4 | -1 | $1,159 | $31,808 | 3 | N/A | false | false |
