| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Avatar | $53,128 | -14.6% | 14 | - | $3,794 | $1,272,973 | 8 | 20th Century Fox International | false | false |
| 2 | 2 | Old Dogs | $21,830 | -29.7% | 5 | - | $4,366 | $59,739 | 2 | Walt Disney Pictures | false | false |
| 3 | 3 | Tooth Fairy | $12,454 | -24.5% | 6 | -2 | $2,075 | $138,800 | 4 | 20th Century Fox International | false | false |
| 4 | - | Saw VI | $9,951 | - | 4 | - | $2,487 | $9,951 | 1 | Walt Disney Pictures | true | false |
| 5 | - | Invictus | $9,179 | - | 4 | - | $2,294 | $9,179 | 1 | Warner Bros. | true | false |
| 6 | 4 | Sherlock Holmes | $8,987 | -33.7% | 6 | -1 | $1,497 | $120,002 | 4 | Warner Bros. | false | false |
| 7 | 5 | Drag Me to Hell | $5,696 | -32.1% | 5 | - | $1,139 | $18,328 | 2 | Universal Pictures International (UPI) | false | false |
| 8 | 7 | Search for Paradise | $5,042 | -34.9% | 4 | - | $1,260 | $98,254 | 5 | N/A | false | false |
| 9 | 6 | Alvin and the Chipmunks: The Squeakquel | $4,360 | -46.8% | 5 | -1 | $872 | $270,413 | 7 | 20th Century Fox International | false | false |
| 10 | 9 | Nine | $3,189 | -45.9% | 3 | -1 | $1,063 | $25,706 | 3 | Sony Pictures Releasing | false | false |
| 11 | 10 | The Twilight Saga: New Moon | $2,299 | -58.8% | 5 | -1 | $459 | $203,967 | 6 | - | false | false |
| 12 | 8 | Armored | $2,146 | -64.3% | 3 | -1 | $715 | $10,323 | 2 | Sony Pictures Releasing | false | false |
| 13 | 12 | Planet 51 | $1,874 | -20.9% | 2 | - | $937 | $39,030 | 5 | - | false | false |
| 14 | 11 | The Princess and the Frog | $1,791 | -51.5% | 7 | - | $255 | $138,395 | 6 | Walt Disney Pictures | false | false |
