| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Avatar | $658,845 | -23.4% | 136 | -12 | $4,844 | $11,242,940 | 7 | 20th Century Fox International | false | false |
| 2 | - | The Wolfman | $355,006 | - | 58 | - | $6,120 | $425,348 | 1 | Universal Pictures International (UPI) | true | false |
| 3 | - | Valentine's Day | $343,398 | - | 58 | - | $5,920 | $343,398 | 1 | Warner Bros. | true | false |
| 4 | 3 | Sherlock Holmes | $145,401 | -47.8% | 95 | -2 | $1,530 | $2,434,611 | 5 | Warner Bros. | false | false |
| 5 | 2 | Toy Story 2009 Re-release | $128,805 | -53.9% | 30 | - | $4,293 | $523,246 | 2 | Walt Disney Pictures | false | false |
| 6 | 4 | Old Dogs | $125,803 | -45.4% | 65 | -1 | $1,935 | $1,149,094 | 4 | Walt Disney Pictures | false | false |
| 7 | 6 | Invictus | $94,546 | -49.8% | 47 | - | $2,011 | $652,193 | 3 | Warner Bros. | false | false |
| 8 | - | Law Abiding Citizen | $83,178 | - | 42 | - | $1,980 | $83,178 | 1 | Alfa Films | true | false |
| 9 | 5 | The Hurt Locker | $78,077 | -59.8% | 50 | +2 | $1,561 | $322,907 | 2 | Distribution Company | false | false |
| 10 | 7 | Tooth Fairy | $76,818 | -55.7% | 46 | -3 | $1,669 | $314,519 | 2 | 20th Century Fox International | false | false |
| 11 | - | Precious | $76,086 | - | 25 | - | $3,043 | $76,086 | 1 | N/A | true | false |
| 12 | 8 | Alvin and the Chipmunks: The Squeakquel | $70,250 | -53.1% | 98 | +3 | $716 | $911,679 | 4 | 20th Century Fox International | false | false |
| 13 | 9 | Up in the Air | $45,217 | -59.7% | 41 | -9 | $1,102 | $645,689 | 4 | Paramount Pictures International | false | false |
| 14 | 11 | It's Complicated | $43,716 | -47.9% | 51 | -7 | $857 | $1,231,431 | 6 | Universal Pictures International (UPI) | false | false |
| 15 | 10 | The Princess and the Frog | $40,330 | -60% | 67 | -34 | $601 | $1,846,341 | 6 | Walt Disney Pictures | false | false |
| 16 | 12 | An Education | $30,826 | -60.2% | 14 | -1 | $2,201 | $129,836 | 2 | Sony Pictures Releasing | false | false |
| 17 | 14 | Daybreakers | $18,383 | -70.8% | 26 | -6 | $707 | $360,925 | 4 | Distribution Company | false | false |
| 18 | 13 | Nine | $9,744 | -85.1% | 10 | -15 | $974 | $246,278 | 3 | Sony Pictures Releasing | false | false |
| 19 | 15 | Astro Boy | $9,115 | -74.6% | 16 | -13 | $569 | $135,578 | 3 | Alfa Films | false | false |
| 20 | 19 | The Secret in Their Eyes | $7,512 | -17.3% | 16 | +3 | $469 | $9,214,986 | 27 | Distribution Company | false | false |
| 21 | 18 | Nora's Will | $4,697 | -50.7% | 6 | -5 | $782 | $41,077 | 3 | Primer Plano Film Group | false | false |
| 22 | 17 | The Young Victoria | $4,689 | -58% | 9 | -5 | $521 | $166,667 | 5 | Distribution Company | false | false |
| 23 | 22 | Ninja Assassin | $3,022 | -35.3% | 8 | -1 | $377 | $123,425 | 6 | Warner Bros. | false | false |
| 24 | - | Andres Doesn't Want to Take a Nap | $2,148 | - | 6 | - | $358 | $9,216 | 2 | Primer Plano Film Group | false | false |
| 25 | - | The Wind Journeys | $1,865 | - | 2 | - | $932 | $1,865 | 1 | Primer Plano Film Group | true | false |
| 26 | 16 | Zombieland | $1,789 | -91.2% | 3 | -15 | $596 | $89,126 | 3 | Sony Pictures Releasing | false | false |
| 27 | 24 | Jellyfish 2010 Re-release | $1,725 | -54.6% | 3 | -1 | $575 | $23,709 | 4 | N/A | false | false |
| 28 | 20 | 2012 | $1,443 | -80.5% | 4 | -7 | $360 | $4,035,113 | 11 | Sony Pictures Releasing | false | false |
| 29 | 23 | Paranormal Activity | $1,393 | -69.3% | 3 | -5 | $464 | $1,269,454 | 10 | Distribution Company | false | false |
| 30 | 33 | The Twilight Saga: New Moon | $1,270 | +279.1% | 7 | +5 | $181 | $3,301,481 | 13 | Alfa Films | false | false |
| 31 | 28 | Let the Right One In | $750 | -23.9% | 4 | +1 | $187 | $172,087 | 11 | Pachamama Cine | false | false |
| 32 | 25 | Easy Virtue | $569 | -83.7% | 4 | -4 | $142 | $95,908 | 5 | Sony Pictures Releasing | false | false |
| 33 | 26 | Departures | $557 | -47.2% | 3 | -1 | $185 | $18,838 | 5 | Alfa Films | false | false |
| 34 | 21 | Halloween II | $544 | -90.3% | 1 | -10 | $544 | $119,336 | 6 | Distribution Company | false | false |
| 35 | 27 | Le code a changé | $451 | -56.6% | 2 | - | $225 | $134,333 | 7 | Alfa Films | false | false |
| 36 | 34 | Let it Rain | $266 | -11.9% | 1 | - | $266 | $139,605 | 10 | Alfa Films | false | false |
| 37 | 35 | Broken Embraces | $151 | -14.7% | 1 | - | $151 | $520,138 | 20 | Universal Pictures International (UPI) | false | false |
| 38 | 36 | Inglourious Basterds | $141 | +42.4% | 1 | - | $141 | $1,224,542 | 24 | Universal Pictures International (UPI) | false | false |
| 39 | 37 | Acne | $46 | -49.5% | 1 | - | $46 | $3,839 | 6 | Primer Plano Film Group | false | false |
