| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Avatar | $362,113 | -17.5% | 80 | +2 | $4,526 | $8,730,417 | 9 | 20th Century Fox International | false | false |
| 2 | - | Valentine's Day | $286,566 | - | 40 | - | $7,164 | $286,566 | 1 | Warner Bros. | true | false |
| 3 | 2 | The Princess and the Frog | $248,660 | -39.4% | 68 | - | $3,656 | $704,389 | 2 | Walt Disney Pictures | false | false |
| 4 | - | Cloudy with a Chance of Meatballs | $198,583 | - | 52 | - | $3,818 | $198,583 | 1 | Sony Pictures Releasing | true | false |
| 5 | 3 | Invictus | $166,012 | -20.6% | 44 | +5 | $3,773 | $749,056 | 3 | Warner Bros. | false | false |
| 6 | 4 | Up in the Air | $139,377 | -24.4% | 54 | - | $2,581 | $1,084,009 | 4 | Zon Lusomundo Audiovisuais | false | false |
| 7 | - | Percy Jackson & the Olympians: The Lightning Thief | $124,220 | - | 29 | - | $4,283 | $124,220 | 1 | Castello Lopes Multimédia | true | false |
| 8 | 5 | The Men Who Stare at Goats | $111,688 | -29.5% | 32 | +2 | $3,490 | $309,221 | 2 | Prisvídeo | false | false |
| 9 | 6 | Whatever Works | $92,460 | -9.2% | 20 | - | $4,623 | $230,281 | 2 | Zon Lusomundo Audiovisuais | false | false |
| 10 | - | Precious | $55,490 | - | 13 | - | $4,268 | $55,490 | 1 | N/A | true | false |
| 11 | 9 | Nine | $26,183 | -39.6% | 28 | -2 | $935 | $516,425 | 5 | Castello Lopes Multimédia | false | false |
| 12 | 8 | Alvin and the Chipmunks: The Squeakquel | $24,349 | -45.6% | 13 | -16 | $1,873 | $1,261,419 | 8 | 20th Century Fox International | false | false |
| 13 | 12 | The Code | $19,949 | +26% | 11 | +2 | $1,813 | $152,962 | 5 | Zon Lusomundo Audiovisuais | false | false |
| 14 | 7 | Sherlock Holmes | $17,329 | -63.5% | 15 | -13 | $1,155 | $2,568,777 | 8 | Warner Bros. | false | false |
| 15 | 14 | Agora | $11,312 | -14.2% | 11 | -128 | $1,028 | $552,339 | 10 | Castello Lopes Multimédia | false | false |
| 16 | 10 | Did You Hear About the Morgans? | $10,962 | -53.7% | 12 | -9 | $913 | $711,587 | 6 | Sony Pictures Releasing | false | false |
| 17 | 11 | Old Dogs | $10,393 | -54.1% | 9 | -9 | $1,154 | $764,362 | 7 | Walt Disney Pictures | false | false |
| 18 | - | My One and Only | $9,289 | - | 6 | - | $1,548 | $9,289 | 1 | Zon Lusomundo Audiovisuais | true | false |
| 19 | 13 | Antichrist | $7,021 | -53% | 5 | -4 | $1,404 | $60,342 | 3 | Prisvídeo | false | false |
| 20 | 17 | Couples Retreat | $6,036 | -22.3% | 7 | -1 | $862 | $1,312,763 | 11 | Zon Lusomundo Audiovisuais | false | false |
| 21 | 22 | Arthur and the Revenge of Maltazard | $1,598 | -20% | 4 | +1 | $399 | $837,973 | 10 | Zon Lusomundo Audiovisuais | false | false |
| 22 | 20 | Julie & Julia | $1,553 | -48.5% | 2 | -1 | $776 | $495,866 | 13 | Sony Pictures Releasing | false | false |
| 23 | 16 | The Road | $1,305 | -86.8% | 2 | -9 | $652 | $276,107 | 6 | Zon Lusomundo Audiovisuais | false | false |
| 24 | 23 | The Twilight Saga: New Moon | $1,103 | +100.9% | 2 | - | $551 | $3,509,504 | 12 | Zon Lusomundo Audiovisuais | false | false |
| 25 | 21 | Bright Star | $837 | -70.8% | 1 | -3 | $837 | $88,929 | 6 | Prisvídeo | false | false |
| 26 | 19 | Where the Wild Things Are | $50 | -98.6% | 2 | -6 | $25 | $98,403 | 6 | Warner Bros. | false | false |
