| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 2 | Avatar | $1,231,173 | +1.9% | 309 | -51 | $3,984 | $49,149,053 | 10 | 20th Century Fox International | false | false |
| 2 | 1 | Percy Jackson & the Olympians: The Lightning Thief | $1,189,798 | -10.7% | 284 | -18 | $4,189 | $2,746,803 | 2 | 20th Century Fox International | false | false |
| 3 | - | Valentine's Day | $1,045,005 | - | 160 | - | $6,531 | $1,045,005 | 1 | Warner Bros. | true | false |
| 4 | 3 | The Wolfman | $666,213 | -15.1% | 264 | -25 | $2,523 | $1,563,568 | 2 | Universal Pictures International (UPI) | false | false |
| 5 | - | The Lovely Bones | $561,428 | - | 175 | - | $3,208 | $561,428 | 1 | Paramount Pictures International | true | false |
| 6 | 4 | The Final Destination | $383,077 | -10.5% | 228 | -18 | $1,680 | $3,626,793 | 3 | PlayArte Pictures | false | false |
| 7 | 5 | Alvin and the Chipmunks: The Squeakquel | $304,267 | -12.4% | 341 | -11 | $892 | $19,589,432 | 7 | 20th Century Fox International | false | false |
| 8 | 6 | Up in the Air | $195,821 | -28.8% | 140 | -12 | $1,398 | $3,587,027 | 5 | Paramount Pictures International | false | false |
| 9 | 7 | Sherlock Holmes | $192,390 | -24.8% | 180 | -46 | $1,068 | $11,341,067 | 7 | Warner Bros. | false | false |
| 10 | 9 | Tooth Fairy | $174,141 | -0.8% | 154 | -23 | $1,130 | $4,076,654 | 5 | 20th Century Fox International | false | false |
| 11 | 8 | Invictus | $129,291 | -27.8% | 66 | -16 | $1,958 | $1,231,810 | 4 | Warner Bros. | false | false |
| 12 | 11 | Precious | $91,467 | -37% | 66 | -2 | $1,385 | $426,104 | 2 | PlayArte Pictures | false | false |
| 13 | 10 | Edge of Darkness | $89,070 | -42.2% | 125 | -17 | $712 | $1,858,764 | 4 | N/A | false | false |
| 14 | 12 | High School Musical: O Desafio | $80,917 | -24.3% | 160 | -41 | $505 | $823,824 | 3 | Walt Disney Pictures | false | false |
| 15 | - | An Education | $65,496 | - | 13 | - | $5,038 | $83,996 | 1 | Sony Pictures Releasing | true | false |
| 16 | 13 | The White Ribbon | $59,938 | -9.3% | 26 | +1 | $2,305 | $209,887 | 2 | N/A | false | false |
| 17 | 15 | Xuxa and the Mystery of the Little Ugly Princess | $43,299 | +33.2% | 147 | -22 | $294 | $4,258,164 | 9 | PlayArte Pictures | false | false |
| 18 | - | The Messenger | $36,626 | - | 20 | - | $1,831 | $46,562 | 1 | Paris Filmes | true | false |
| 19 | 14 | The Hurt Locker | $15,882 | -61.9% | 33 | -9 | $481 | $257,584 | 3 | N/A | false | false |
| 20 | 16 | Nine | $11,676 | -55% | 15 | -3 | $778 | $433,172 | 4 | Sony Pictures Releasing | false | false |
| 21 | 17 | Zombieland | $9,490 | -39.6% | 12 | -2 | $790 | $279,327 | 4 | Sony Pictures Releasing | false | false |
| 22 | 19 | Where the Wild Things Are | $8,119 | -22.3% | 10 | -8 | $811 | $377,672 | 6 | Warner Bros. | false | false |
| 23 | 20 | Julie & Julia | $8,042 | -19.1% | 20 | +1 | $402 | $1,231,093 | 13 | Sony Pictures Releasing | false | false |
| 24 | 24 | Astro Boy | $7,441 | +23% | 26 | -9 | $286 | $475,965 | 5 | Paris Filmes | false | false |
| 25 | 21 | The Fourth Kind | $6,499 | -31.5% | 21 | -4 | $309 | $872,973 | 8 | N/A | false | false |
| 26 | 25 | Broken Embraces | $6,331 | +5.8% | 15 | - | $422 | $1,367,858 | 12 | Universal Pictures International (UPI) | false | false |
| 27 | 27 | Lula, the Son of Brazil | $4,974 | +37.7% | 27 | -3 | $184 | $3,770,539 | 8 | Europa Filmes | false | false |
| 28 | 18 | Ninja Assassin | $4,772 | -62.2% | 23 | -22 | $207 | $112,002 | 3 | Warner Bros. | false | false |
| 29 | 22 | Management | $4,246 | -37.2% | 12 | -1 | $353 | $483,303 | 11 | N/A | false | false |
| 30 | 29 | Hachi: A Dog's Tale | $4,085 | +30.2% | 25 | -3 | $163 | $3,502,608 | 9 | N/A | false | false |
| 31 | 23 | Chéri | $2,518 | -58.6% | 8 | -5 | $314 | $188,916 | 5 | N/A | false | false |
| 32 | 30 | Easy Virtue | $2,390 | +14.7% | 3 | - | $796 | $175,797 | 18 | Sony Pictures Releasing | false | false |
| 33 | 28 | The Princess and the Frog | $2,132 | -34% | 15 | -12 | $142 | $3,796,260 | 11 | Walt Disney Pictures | false | false |
| 34 | 31 | 2012 | $787 | -44.8% | 6 | +1 | $131 | $25,651,563 | 15 | Sony Pictures Releasing | false | false |
| 35 | 34 | A Christmas Carol | $400 | +1,190.3% | 3 | +1 | $133 | $2,923,409 | 16 | Walt Disney Pictures | false | false |
| 36 | 35 | Saw VI | $146 | +440.7% | 1 | - | $146 | $1,733,289 | 16 | Walt Disney Pictures | false | false |
| 37 | 33 | The Assailant | $76 | +55.1% | 3 | +2 | $25 | $2,019,443 | 17 | Walt Disney Pictures | false | false |
