| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 2 | Avatar | $57,006 | -17.7% | 21 | - | $2,714 | $1,469,539 | 10 | 20th Century Fox International | false | false |
| 2 | - | The Wolfman | $49,581 | - | 9 | - | $5,509 | $49,581 | 1 | United International Pictures | true | false |
| 3 | - | Dear John | $31,947 | - | 6 | - | $5,324 | $31,947 | 1 | N/A | true | false |
| 4 | 1 | Valentine's Day | $30,718 | -57.3% | 10 | - | $3,071 | $118,825 | 2 | Warner Bros. | false | false |
| 5 | 5 | Alvin and the Chipmunks: The Squeakquel | $20,670 | -2% | 8 | - | $2,583 | $45,293 | 2 | 20th Century Fox International | false | false |
| 6 | 7 | Cloudy with a Chance of Meatballs | $19,893 | +2% | 16 | - | $1,243 | $77,659 | 3 | Sony Pictures Releasing | false | false |
| 7 | 3 | Up in the Air | $17,982 | -35.4% | 7 | - | $2,568 | $103,542 | 3 | United International Pictures | false | false |
| 8 | 4 | It's Complicated | $17,372 | -29.4% | 7 | - | $2,481 | $143,944 | 4 | United International Pictures | false | false |
| 9 | 6 | The Book of Eli | $11,805 | -41.3% | 7 | -1 | $1,686 | $204,086 | 5 | N/A | false | false |
| 10 | 8 | The Princess and the Frog | $11,212 | -1.7% | 10 | - | $1,121 | $139,899 | 5 | Walt Disney Pictures | false | false |
| 11 | 10 | Did You Hear About the Morgans? | $3,574 | -17.5% | 8 | - | $446 | $126,579 | 6 | Sony Pictures Releasing | false | false |
| 12 | 9 | Paranormal Activity | $3,223 | -70.6% | 5 | - | $644 | $68,085 | 4 | N/A | false | false |
| 13 | 11 | An Education | $3,081 | -18.6% | 4 | - | $770 | $38,276 | 5 | N/A | false | false |
| 14 | - | Hachi: A Dog's Tale | $2,093 | - | 1 | - | $2,093 | $2,093 | 1 | N/A | true | false |
| 15 | 12 | Everybody's Fine | $1,918 | -47.2% | 1 | - | $1,918 | $6,459 | 2 | Walt Disney Pictures | false | false |
| 16 | 14 | Moon | $1,148 | -40.1% | 2 | - | $574 | $15,396 | 4 | N/A | false | false |
