| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Prince of the Seas | $271,754 | - | 23 | - | $11,815 | $271,754 | 1 | Gulf Film | true | false |
| 2 | - | Saw VI | $146,460 | - | 24 | - | $6,102 | $146,460 | 1 | Gulf Film | true | false |
| 3 | 1 | My Name Is Khan | $138,357 | -65.2% | 23 | -9 | $6,015 | $1,963,629 | 3 | 20th Century Fox International | false | false |
| 4 | - | Percy Jackson & the Olympians: The Lightning Thief | $131,849 | - | 23 | - | $5,732 | $165,921 | 1 | 20th Century Fox International | true | false |
| 5 | 4 | Avatar | $118,026 | -24.3% | 11 | -1 | $10,729 | $7,003,656 | 11 | 20th Century Fox International | false | false |
| 6 | - | When in Rome | $115,406 | - | 25 | - | $4,616 | $115,406 | 1 | Walt Disney Pictures | true | false |
| 7 | 3 | From Paris with Love | $108,828 | -57.8% | 19 | -7 | $5,727 | $441,713 | 2 | Italian International Film | false | false |
| 8 | 2 | The Wolfman | $95,153 | -64.2% | 25 | -1 | $3,806 | $435,848 | 2 | United International Pictures | false | false |
| 9 | 5 | The Spy Next Door 2010 Re-release | $63,770 | -55.6% | 22 | -1 | $2,898 | $627,749 | 3 | Gulf Film | false | false |
| 10 | 6 | Valentine's Day | $43,006 | -56.4% | 6 | -6 | $7,167 | $576,999 | 3 | Warner Bros. | false | false |
| 11 | - | The Lovely Bones | $40,969 | - | 20 | - | $2,048 | $40,969 | 1 | United International Pictures | true | false |
| 12 | 7 | The Blind Side | $33,300 | -65.3% | 6 | -10 | $5,550 | $159,195 | 2 | Warner Bros. | false | false |
| 13 | 8 | The Book of Eli | $17,959 | -62.8% | 4 | -13 | $4,489 | $796,243 | 4 | Gulf Film | false | false |
| 14 | 9 | Law Abiding Citizen | $11,329 | -58.7% | 4 | -10 | $2,832 | $497,503 | 4 | Gulf Film | false | false |
| 15 | 13 | Alvin and the Chipmunks: The Squeakquel | $8,620 | -30.7% | 5 | - | $1,724 | $908,838 | 9 | 20th Century Fox International | false | false |
| 16 | 12 | The Hurt Locker | $3,731 | -72.6% | 1 | -7 | $3,731 | $97,522 | 3 | Gulf Film | false | false |
| 17 | 14 | The Lucky Ones | $3,180 | -59.4% | 7 | +1 | $454 | $14,620 | 2 | Gulf Film | false | false |
| 18 | 18 | Up in the Air | $3,015 | +6.1% | 1 | - | $3,015 | $382,571 | 6 | United International Pictures | false | false |
| 19 | 22 | Sherlock Holmes | $2,556 | +219.5% | 1 | - | $2,556 | $1,652,860 | 10 | Warner Bros. | false | false |
| 20 | 16 | Did You Hear About the Morgans? | $2,132 | -60.7% | 1 | -1 | $2,132 | $354,222 | 5 | Sony Pictures Releasing | false | false |
| 21 | 20 | Ace Ventura: Pet Detective Jr. | $1,887 | +94.7% | 1 | - | $1,887 | $95,035 | 6 | Gulf Film | false | false |
| 22 | 10 | Escaping Tel Aviv | $1,862 | -91.3% | 1 | -7 | $1,862 | $279,959 | 4 | Gulf Film | false | false |
| 23 | 11 | Love N' Dancing | $1,564 | -88.7% | 1 | -13 | $1,564 | $21,666 | 2 | Gulf Film | false | false |
| 24 | 15 | 100 Feet | $534 | -91% | 1 | -5 | $534 | $49,793 | 3 | Gulf Film | false | false |
