| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Shutter Island | $745,373 | - | 46 | - | $16,203 | $846,382 | 1 | Universal Pictures International (UPI) | true | false |
| 2 | 2 | Avatar | $387,360 | -51% | 133 | - | $2,912 | $14,184,069 | 11 | 20th Century Fox International | false | false |
| 3 | 1 | The Princess and the Frog | $285,411 | -72.2% | 65 | +2 | $4,390 | $2,974,376 | 4 | Walt Disney Pictures | false | false |
| 4 | 3 | Percy Jackson & the Olympians: The Lightning Thief | $235,293 | -66.6% | 80 | - | $2,941 | $1,738,422 | 3 | 20th Century Fox International | false | false |
| 5 | 4 | Valentine's Day | $215,109 | -53.6% | 48 | - | $4,481 | $1,316,644 | 3 | 20th Century Fox International | false | false |
| 6 | 5 | Bo | $183,797 | -53.7% | 23 | +2 | $7,991 | $1,014,832 | 3 | Kinepolis Film Distribution (KFD) | false | false |
| 7 | 9 | The Pimp | $155,398 | -38.7% | 18 | - | $8,633 | $433,790 | 2 | Belga Films | false | false |
| 8 | - | From Paris with Love | $153,114 | - | 33 | - | $4,639 | $153,815 | 1 | Belga Films | true | false |
| 9 | 8 | Edge of Darkness | $116,639 | -59.9% | 43 | -1 | $2,712 | $465,344 | 2 | Kinepolis Film Distribution (KFD) | false | false |
| 10 | 6 | The Wolfman | $109,950 | -65.1% | 36 | - | $3,054 | $972,438 | 3 | Universal Pictures International (UPI) | false | false |
| 11 | 7 | Planet 51 | $92,411 | -68.8% | 60 | - | $1,540 | $701,436 | 3 | Belga Films | false | false |
| 12 | - | A Single Man | $87,356 | - | 11 | - | $7,941 | $89,628 | 1 | Cinéart | true | false |
| 13 | 10 | Alvin and the Chipmunks: The Squeakquel | $69,688 | -72.4% | 48 | - | $1,451 | $4,408,221 | 10 | 20th Century Fox International | false | false |
| 14 | 12 | I Love You Phillip Morris | $63,901 | -62.5% | 27 | - | $2,366 | $280,207 | 2 | Belga Films | false | false |
| 15 | 11 | Cloudy with a Chance of Meatballs | $55,195 | -69% | 30 | -3 | $1,839 | $1,036,419 | 7 | Sony Pictures Releasing | false | false |
| 16 | 13 | The Lovely Bones | $46,954 | -64% | 26 | -7 | $1,805 | $465,747 | 3 | Universal Pictures International (UPI) | false | false |
| 17 | 15 | Oceans | $44,243 | -54.6% | 25 | -1 | $1,769 | $650,165 | 5 | Alternative Films | false | false |
| 18 | 14 | Sherlock Holmes | $40,571 | -59.7% | 24 | -14 | $1,690 | $2,780,674 | 8 | Warner Bros. | false | false |
| 19 | 19 | Dossier K. | $36,154 | -45.6% | 15 | -2 | $2,410 | $3,715,763 | 12 | Kinepolis Film Distribution (KFD) | false | false |
| 20 | 16 | The Imaginarium of Doctor Parnassus | $36,028 | -54.1% | 14 | -2 | $2,573 | $320,848 | 3 | Kinepolis Film Distribution (KFD) | false | false |
| 21 | 17 | Up in the Air | $35,000 | -53.4% | 16 | -2 | $2,187 | $1,095,149 | 6 | Universal Pictures International (UPI) | false | false |
| 22 | 20 | Gainsbourg: A Heroic Life | $32,091 | -49.1% | 21 | - | $1,528 | $428,313 | 4 | Cinéart | false | false |
| 23 | - | An Education | $29,712 | - | 8 | - | $3,714 | $36,598 | 1 | Kinepolis Film Distribution (KFD) | true | false |
| 24 | 21 | A Serious Man | $27,491 | -38.2% | 12 | +1 | $2,290 | $441,904 | 6 | Universal Pictures International (UPI) | false | false |
| 25 | 24 | Invictus | $20,917 | -34.9% | 14 | +6 | $1,494 | $727,223 | 7 | Warner Bros. | false | false |
| 26 | 18 | The Book of Eli | $20,116 | -71.7% | 18 | -8 | $1,117 | $555,312 | 4 | Paradiso Entertainment | false | false |
| 27 | 27 | Mr. Nobody | $16,440 | -29.5% | 13 | -2 | $1,264 | $812,825 | 7 | Belga Films | false | false |
| 28 | - | The Boat Race | $12,791 | - | 6 | - | $2,131 | $18,751 | 1 | Cinéart | true | false |
| 29 | 26 | Vincere | $12,580 | -47.6% | 8 | - | $1,572 | $70,515 | 3 | ABC Distribution | false | false |
| 30 | 22 | Fantastic Mr. Fox | $12,433 | -69.5% | 17 | - | $731 | $57,472 | 2 | 20th Century Fox International | false | false |
| 31 | 25 | Plop en de kabouterbaby | $9,356 | -70.8% | 11 | -3 | $850 | $1,540,037 | 12 | Kinepolis Film Distribution (KFD) | false | false |
| 32 | 23 | Did You Hear About the Morgans? | $9,272 | -75.5% | 14 | -4 | $662 | $750,923 | 5 | Sony Pictures Releasing | false | false |
| 33 | 28 | Anubis en de wraak van Arghus | $6,642 | -70.2% | 5 | -1 | $1,328 | $1,053,397 | 11 | Kinepolis Film Distribution (KFD) | false | false |
| 34 | 30 | OceanWorld | $5,131 | -72.5% | 7 | - | $733 | $70,623 | 3 | N/A | false | false |
| 35 | 41 | The Concert | $4,610 | +6.9% | 12 | +2 | $384 | $831,037 | 16 | Cinéart | false | false |
| 36 | - | Mary and Max | $4,253 | - | 3 | - | $1,417 | $5,291 | 1 | Kinepolis Film Distribution (KFD) | true | false |
| 37 | 29 | The Road | $3,934 | -79.4% | 13 | - | $302 | $365,488 | 5 | Benelux Film Distributors | false | false |
| 38 | 32 | The Girl Who Played with Fire | $3,504 | -66.7% | 7 | - | $500 | $190,969 | 7 | Benelux Film Distributors | false | false |
| 39 | - | Hadewijch | $3,247 | - | 5 | - | $649 | $3,788 | 1 | N/A | true | false |
| 40 | 33 | Silent Voice | $3,141 | -65.9% | 4 | - | $785 | $14,813 | 2 | Cinéart | false | false |
| 41 | 37 | Paranormal Activity | $3,040 | -54.1% | 5 | -2 | $608 | $1,155,278 | 14 | Kinepolis Film Distribution (KFD) | false | false |
| 42 | 34 | It's Complicated | $2,795 | -67.7% | 5 | +2 | $559 | $1,459,580 | 10 | Universal Pictures International (UPI) | false | false |
| 43 | 31 | The Barons | $2,739 | -74.5% | 9 | -2 | $304 | $1,294,382 | 17 | Cinéart | false | false |
| 44 | 39 | No One Knows About Persian Cats | $2,615 | -47.9% | 3 | - | $871 | $51,603 | 5 | Cinéart | false | false |
| 45 | 36 | Angel at Sea | $2,367 | -65.1% | 3 | - | $789 | $22,069 | 3 | N/A | false | false |
| 46 | 42 | Das Lied der Dinge | $2,261 | -26.5% | 3 | - | $753 | $3,589,842 | 21 | Kinepolis Film Distribution (KFD) | false | false |
| 47 | 44 | Altiplano | $2,229 | -26.5% | 4 | +1 | $557 | $154,835 | 14 | N/A | false | false |
| 48 | - | Eastern Plays | $1,102 | - | 2 | - | $551 | $1,858 | 1 | N/A | true | false |
| 49 | - | Katalin Varga | $960 | - | 1 | - | $960 | $1,180 | 1 | Benelux Film Distributors | true | false |
| 50 | 48 | The Ordinary People | $861 | -42.2% | 4 | - | $215 | $29,091 | 6 | Cinéart | false | false |
