| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Avatar | $24,587 | -14.4% | 10 | - | $2,458 | $1,400,828 | 11 | 20th Century Fox International | false | false |
| 2 | 3 | Percy Jackson & the Olympians: The Lightning Thief | $18,807 | -16% | 11 | -1 | $1,709 | $83,447 | 3 | 20th Century Fox International | false | false |
| 3 | 2 | The Wolfman | $18,166 | -34.4% | 11 | -1 | $1,651 | $104,841 | 3 | Universal Pictures International (UPI) | false | false |
| 4 | - | Edge of Darkness | $14,338 | - | 7 | - | $2,048 | $14,338 | 1 | Warner Bros. | true | false |
| 5 | 4 | Toy Story 2 2009 Re-release | $13,116 | -22.4% | 4 | - | $3,279 | $32,064 | 2 | Walt Disney Pictures | false | false |
| 6 | 5 | Old Dogs | $10,970 | -20.9% | 4 | - | $2,742 | $114,318 | 5 | Walt Disney Pictures | false | false |
| 7 | - | All About Steve | $8,184 | - | 4 | - | $2,046 | $8,184 | 1 | 20th Century Fox International | true | false |
| 8 | 7 | The Hurt Locker | $7,088 | -4.7% | 2 | - | $3,544 | $16,875 | 2 | - | false | false |
| 9 | - | Sorority Row | $7,030 | - | 6 | - | $1,171 | $7,030 | 1 | - | true | false |
| 10 | 6 | Valentine's Day | $5,573 | -53.6% | 4 | -1 | $1,393 | $41,041 | 3 | Warner Bros. | false | false |
| 11 | - | Couples Retreat | $5,226 | - | 4 | - | $1,306 | $5,226 | 1 | Universal Pictures International (UPI) | true | false |
| 12 | 9 | Tooth Fairy | $4,763 | -24.1% | 4 | - | $1,190 | $164,273 | 7 | 20th Century Fox International | false | false |
| 13 | 11 | Toy Story 2009 Re-release | $4,676 | +26.3% | 3 | - | $1,558 | $32,214 | 3 | Walt Disney Pictures | false | false |
| 14 | 10 | Invictus | $2,171 | -52.5% | 2 | -1 | $1,085 | $29,852 | 4 | Warner Bros. | false | false |
| 15 | 8 | Ninja Assassin | $2,074 | -71.7% | 2 | -2 | $1,037 | $11,662 | 2 | Warner Bros. | false | false |
| 16 | - | The Host 2010 Re-release | $1,546 | - | 2 | - | $773 | $1,546 | 1 | N/A | true | false |
| 17 | 12 | Flawless | $1,188 | -61% | 2 | - | $594 | $4,738 | 2 | - | false | false |
| 18 | 14 | Sherlock Holmes | $952 | -49% | 1 | -1 | $952 | $130,373 | 7 | Warner Bros. | false | false |
| 19 | 13 | Saw VI | $697 | -76% | 1 | -3 | $697 | $27,674 | 4 | Walt Disney Pictures | false | false |
