| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Old Dogs | $108,401 | -22.3% | 28 | - | $3,871 | $373,059 | 2 | Walt Disney Pictures | false | false |
| 2 | 2 | Percy Jackson & the Olympians: The Lightning Thief | $96,520 | -14.2% | 31 | - | $3,113 | $317,587 | 2 | 20th Century Fox International | false | false |
| 3 | - | Valentine's Day | $57,350 | - | 28 | - | $2,048 | $247,255 | 2 | - | false | false |
| 4 | 3 | Tooth Fairy | $43,416 | -31.2% | 31 | - | $1,400 | $627,664 | 4 | 20th Century Fox International | false | false |
| 5 | 4 | Avatar | $37,907 | -22.2% | 26 | -3 | $1,457 | $2,584,607 | 10 | 20th Century Fox International | false | false |
| 6 | 5 | Toy Story 2 2009 Re-release | $28,260 | -31.1% | 13 | -1 | $2,173 | $215,398 | 3 | Walt Disney Pictures | false | false |
| 7 | 6 | Couples Retreat | $19,928 | -21.3% | 15 | - | $1,328 | $67,391 | 2 | United International Pictures | false | false |
| 8 | - | Over Her Dead Body | $11,245 | - | 7 | - | $1,606 | $53,374 | 8 | - | false | false |
| 9 | - | Invictus | $9,315 | - | 8 | - | $1,164 | $9,315 | 1 | - | true | false |
| 10 | - | The Secret in Their Eyes | $5,441 | - | 5 | - | $1,088 | $5,441 | 1 | N/A | true | false |
| 11 | - | Sherlock Holmes | $4,595 | - | 6 | - | $765 | $533,654 | 6 | - | false | false |
| 12 | 7 | Everybody's Fine | $3,469 | +24.1% | 12 | - | $289 | $69,117 | 4 | Walt Disney Pictures | false | false |
| 13 | - | Pride and Glory | $3,136 | - | 4 | - | $784 | $44,695 | 14 | - | false | false |
| 14 | - | Coco Before Chanel | $2,481 | - | 9 | - | $275 | $51,589 | 10 | - | false | false |
| 15 | 10 | The Princess and the Frog | $1,709 | +14.8% | 14 | +1 | $122 | $761,189 | 9 | Walt Disney Pictures | false | false |
| 16 | 9 | Nine | $1,425 | -20.4% | 3 | -3 | $475 | $28,741 | 4 | Sony Pictures Releasing | false | false |
| 17 | - | The Informant! | $1,296 | - | 7 | - | $185 | $19,816 | 3 | - | false | false |
| 18 | 11 | Alvin and the Chipmunks: The Squeakquel | $512 | -56.2% | 6 | -5 | $85 | $780,163 | 9 | 20th Century Fox International | false | false |
