| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Alice in Wonderland | $83,271 | - | 8 | - | $10,408 | $83,271 | 1 | Walt Disney Pictures | true | false |
| 2 | 1 | Avatar | $30,073 | -49.9% | 5 | -1 | $6,014 | $1,607,071 | 12 | 20th Century Fox International | false | false |
| 3 | 3 | From Paris with Love | $24,490 | -34.9% | 7 | - | $3,498 | $124,881 | 3 | Italian International Film | false | false |
| 4 | 5 | When in Rome | $18,443 | -20.8% | 7 | - | $2,634 | $49,519 | 2 | Walt Disney Pictures | false | false |
| 5 | 2 | Percy Jackson & the Olympians: The Lightning Thief | $16,781 | -56.5% | 7 | - | $2,397 | $61,449 | 2 | 20th Century Fox International | false | false |
| 6 | 4 | Valentine's Day | $15,654 | -46.6% | 6 | - | $2,609 | $205,398 | 4 | Warner Bros. | false | false |
| 7 | 6 | The Wolfman | $13,311 | -39.9% | 6 | -1 | $2,218 | $94,333 | 3 | United International Pictures | false | false |
| 8 | - | The Road | $9,454 | - | 5 | - | $1,890 | $9,454 | 1 | N/A | true | false |
| 9 | 8 | The Book of Eli | $8,256 | -34.1% | 4 | - | $2,064 | $196,142 | 7 | Jaguar Film International Distribution | false | false |
| 10 | 9 | Edge of Darkness | $8,230 | -19.6% | 2 | - | $4,115 | $98,809 | 5 | N/A | false | false |
| 11 | 11 | Did You Hear About the Morgans? | $3,747 | -26.1% | 3 | - | $1,249 | $111,947 | 6 | Sony Pictures Releasing | false | false |
