| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Alice in Wonderland | $85,902 | -34.1% | 13 | +1 | $6,607 | $486,109 | 3 | Walt Disney Pictures | false | false |
| 2 | - | The Book of Eli | $21,124 | - | 6 | - | $3,520 | $21,124 | 1 | Sony Pictures Releasing | true | false |
| 3 | - | The Blind Side | $10,210 | - | 5 | - | $2,042 | $10,210 | 1 | Warner Bros. | true | false |
| 4 | 2 | The Hurt Locker | $8,003 | -46.1% | 2 | - | $4,001 | $57,325 | 5 | - | false | false |
| 5 | 6 | Percy Jackson & the Olympians: The Lightning Thief | $6,175 | -9.6% | 5 | -1 | $1,235 | $116,807 | 6 | 20th Century Fox International | false | false |
| 6 | 5 | Cirque du Freak: The Vampire's Assistant | $6,115 | -19.8% | 7 | +1 | $873 | $17,244 | 2 | Universal Pictures International (UPI) | false | false |
| 7 | 4 | Did You Hear About the Morgans? | $5,503 | -32.9% | 4 | - | $1,375 | $15,923 | 2 | Sony Pictures Releasing | false | false |
| 8 | 7 | The Wolfman | $5,425 | -20.6% | 4 | -2 | $1,356 | $142,291 | 6 | Universal Pictures International (UPI) | false | false |
| 9 | 10 | Old Dogs | $3,549 | +31.9% | 4 | +1 | $887 | $133,298 | 8 | Walt Disney Pictures | false | false |
| 10 | 8 | Edge of Darkness | $3,244 | -49.6% | 4 | -2 | $811 | $43,039 | 4 | Warner Bros. | false | false |
| 11 | 3 | Avatar | $2,487 | -72.9% | 5 | -3 | $497 | $1,460,086 | 14 | 20th Century Fox International | false | false |
| 12 | - | Everybody's Fine | $1,699 | - | 2 | - | $849 | $1,699 | 1 | Walt Disney Pictures | true | false |
