| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Shutter Island | $40,978 | -37% | 9 | - | $4,553 | $129,572 | 2 | United International Pictures | false | false |
| 2 | 2 | Alice in Wonderland | $36,928 | -26.6% | 13 | -1 | $2,840 | $184,827 | 3 | Walt Disney Pictures | false | false |
| 3 | - | From Paris with Love | $23,549 | - | 6 | - | $3,924 | $23,549 | 1 | N/A | true | false |
| 4 | 3 | Avatar | $18,888 | -29.9% | 11 | -2 | $1,717 | $1,611,198 | 14 | 20th Century Fox International | false | false |
| 5 | - | Leap Year | $16,831 | - | 6 | - | $2,805 | $16,831 | 1 | United International Pictures | true | false |
| 6 | - | Percy Jackson & the Olympians: The Lightning Thief | $16,226 | - | 6 | - | $2,704 | $16,226 | 1 | 20th Century Fox International | true | false |
| 7 | 4 | The Blind Side | $9,252 | -48.2% | 6 | - | $1,542 | $65,708 | 3 | Warner Bros. | false | false |
| 8 | 6 | Cloudy with a Chance of Meatballs | $9,144 | -28.6% | 15 | -1 | $609 | $144,837 | 7 | Sony Pictures Releasing | false | false |
| 9 | 7 | The Spy Next Door 2010 Re-release | $6,030 | -47.4% | 5 | - | $1,206 | $56,041 | 4 | N/A | false | false |
| 10 | 10 | Dear John | $3,912 | -36.6% | 6 | - | $652 | $93,463 | 5 | N/A | false | false |
| 11 | 9 | The Lovely Bones | $3,739 | -44.8% | 6 | -1 | $623 | $53,360 | 4 | United International Pictures | false | false |
| 12 | 12 | Alvin and the Chipmunks: The Squeakquel | $3,507 | -32.6% | 8 | - | $438 | $83,991 | 6 | 20th Century Fox International | false | false |
| 13 | 5 | Invictus 2010 Re-release | $3,391 | -77.2% | 6 | - | $565 | $21,690 | 2 | Warner Bros. | false | false |
| 14 | 8 | The Wolfman | $1,673 | -79.8% | 4 | -4 | $418 | $145,585 | 5 | United International Pictures | false | false |
| 15 | - | Crazy Heart | $1,520 | - | 1 | - | $1,520 | $1,520 | 1 | 20th Century Fox International | true | false |
