| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Alice in Wonderland | $737,086 | -34.2% | 118 | +4 | $6,246 | $3,825,657 | 3 | Walt Disney Pictures | false | false |
| 2 | 2 | Shutter Island | $202,124 | -30.8% | 46 | - | $4,394 | $2,586,342 | 5 | Universal Pictures International (UPI) | false | false |
| 3 | - | The Ghost Writer | $190,564 | - | 34 | - | $5,604 | $229,179 | 1 | Benelux Film Distributors | true | false |
| 4 | - | 22 Bullets | $119,302 | - | 15 | - | $7,953 | $125,073 | 1 | Belga Films | true | false |
| 5 | - | Wolf 2010 Re-release | $113,808 | - | 23 | - | $4,948 | $118,388 | 1 | Kinepolis Film Distribution (KFD) | true | false |
| 6 | 3 | Avatar | $101,227 | -35.5% | 57 | -8 | $1,775 | $14,731,374 | 15 | 20th Century Fox International | false | false |
| 7 | 4 | The Round Up | $98,084 | -33.6% | 23 | - | $4,264 | $494,868 | 3 | Belga Films | false | false |
| 8 | 7 | Bo | $61,964 | -32.9% | 23 | - | $2,694 | $1,473,047 | 7 | Kinepolis Film Distribution (KFD) | false | false |
| 9 | 5 | Case 39 | $59,176 | -40.9% | 23 | -1 | $2,572 | $291,202 | 2 | Universal Pictures International (UPI) | false | false |
| 10 | - | All That Glitters | $51,005 | - | 12 | - | $4,250 | $51,005 | 1 | Alternative Films | true | false |
| 11 | 6 | The Princess and the Frog | $49,878 | -47.3% | 63 | +1 | $791 | $3,369,158 | 8 | Walt Disney Pictures | false | false |
| 12 | 8 | The Pimp | $36,895 | -39.8% | 16 | -1 | $2,305 | $770,600 | 6 | Belga Films | false | false |
| 13 | 11 | Percy Jackson & the Olympians: The Lightning Thief | $27,924 | -40.4% | 59 | -4 | $473 | $2,043,013 | 7 | 20th Century Fox International | false | false |
| 14 | 12 | From Paris with Love | $27,052 | -34.3% | 21 | -2 | $1,288 | $422,390 | 5 | Belga Films | false | false |
| 15 | 10 | Desert Flower 2009 Re-release | $26,975 | -47% | 11 | -2 | $2,452 | $151,235 | 2 | Cinéart | false | false |
| 16 | 16 | Edge of Darkness | $26,210 | -28.2% | 18 | -4 | $1,456 | $683,756 | 6 | Kinepolis Film Distribution (KFD) | false | false |
| 17 | 14 | A Single Man | $25,165 | -32.6% | 11 | -1 | $2,287 | $334,548 | 5 | Cinéart | false | false |
| 18 | 13 | Precious | $24,824 | -34.9% | 14 | -2 | $1,773 | $228,365 | 4 | A-Film Distribution | false | false |
| 19 | 20 | Heartbreaker | $20,519 | -16.3% | 21 | - | $977 | $54,720 | 2 | N/A | false | false |
| 20 | 17 | Alvin and the Chipmunks: The Squeakquel | $20,092 | -42.1% | 31 | -1 | $648 | $4,432,010 | 14 | 20th Century Fox International | false | false |
| 21 | 9 | Chloe | $19,754 | -64.9% | 15 | -6 | $1,316 | $197,307 | 3 | Universal Pictures International (UPI) | false | false |
| 22 | 15 | Planet 51 | $15,370 | -58.6% | 40 | -6 | $384 | $848,673 | 7 | Belga Films | false | false |
| 23 | 19 | The Hurt Locker | $14,580 | -42.7% | 6 | -1 | $2,430 | $301,330 | 27 | Belga Films | false | false |
| 24 | 18 | Valentine's Day | $10,839 | -68.6% | 21 | -9 | $516 | $1,580,244 | 7 | 20th Century Fox International | false | false |
| 25 | 23 | The Wolfman | $7,988 | -51.6% | 7 | -15 | $1,141 | $1,088,590 | 7 | Universal Pictures International (UPI) | false | false |
| 26 | 21 | I Love You Phillip Morris | $7,192 | -60.7% | 12 | -7 | $599 | $389,118 | 6 | Belga Films | false | false |
| 27 | 26 | Dossier K. | $6,316 | -51.5% | 4 | -4 | $1,579 | $3,704,896 | 16 | Kinepolis Film Distribution (KFD) | false | false |
| 28 | 30 | Cloudy with a Chance of Meatballs | $6,132 | -35.3% | 7 | -6 | $876 | $1,092,135 | 11 | Sony Pictures Releasing | false | false |
| 29 | 33 | Oceans | $5,545 | -34.3% | 13 | -2 | $426 | $713,505 | 9 | Alternative Films | false | false |
| 30 | 27 | Crazy Heart | $5,499 | -46.9% | 5 | - | $1,099 | $54,732 | 4 | 20th Century Fox International | false | false |
| 31 | 29 | An Education | $5,180 | -45.7% | 8 | - | $647 | $107,283 | 5 | Kinepolis Film Distribution (KFD) | false | false |
| 32 | 25 | Dumas | $4,332 | -72.8% | 8 | - | $541 | $28,640 | 2 | Benelux Film Distributors | false | false |
| 33 | 37 | A Serious Man | $4,025 | -42.9% | 10 | - | $402 | $481,785 | 10 | Universal Pictures International (UPI) | false | false |
| 34 | 38 | The Book of Eli | $3,984 | -31.2% | 2 | -3 | $1,992 | $573,444 | 8 | Paradiso Entertainment | false | false |
| 35 | 40 | Devil's Kickers | $3,676 | -32.9% | 3 | - | $1,225 | $13,416 | 3 | Universal Pictures International (UPI) | false | false |
| 36 | 28 | Pièce montée | $2,894 | -69.7% | 7 | -2 | $413 | $49,215 | 3 | Alternative Films | false | false |
| 37 | 41 | Mr. Nobody | $2,738 | -49.9% | 5 | -4 | $547 | $829,179 | 11 | Belga Films | false | false |
| 38 | 31 | Nine | $2,583 | -72.4% | 5 | -8 | $516 | $189,416 | 4 | Paradiso Entertainment | false | false |
| 39 | 24 | White as Snow | $2,369 | -85.2% | 6 | -2 | $394 | $22,670 | 2 | Benelux Film Distributors | false | false |
| 40 | 43 | Everybody's Fine | $2,189 | -50.1% | 5 | - | $437 | $12,944 | 2 | Walt Disney Pictures | false | false |
| 41 | - | First Mission | $2,183 | - | 2 | - | $1,091 | $2,183 | 1 | Kinepolis Film Distribution (KFD) | true | false |
| 42 | 34 | Coursier | $2,156 | -73.1% | 6 | -6 | $359 | $113,791 | 4 | Belga Films | false | false |
| 43 | 47 | Gainsbourg: A Heroic Life | $1,554 | -20.9% | 5 | -4 | $310 | $462,434 | 8 | Cinéart | false | false |
| 44 | 46 | The Boat Race | $1,532 | -25.8% | 5 | +1 | $306 | $37,657 | 5 | Cinéart | false | false |
| 45 | 45 | Fantastic Mr. Fox | $826 | -62.3% | 9 | -3 | $91 | $74,792 | 6 | 20th Century Fox International | false | false |
| 46 | 52 | The Road | $625 | -33.6% | 4 | - | $156 | $367,861 | 9 | Benelux Film Distributors | false | false |
| 47 | - | Toys in the Attic 2010 Re-release | $568 | - | 3 | - | $189 | $568 | 1 | N/A | true | false |
| 48 | 22 | The Men Who Stare at Goats | $487 | -97.2% | 3 | -3 | $162 | $327,273 | 12 | Kinepolis Film Distribution (KFD) | false | false |
| 49 | 54 | The Girl Who Played with Fire | $91 | -57.9% | 1 | - | $91 | $194,511 | 11 | Benelux Film Distributors | false | false |
