| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Alice in Wonderland | $10,200 | -45.1% | 6 | - | $1,700 | $190,399 | 5 | Walt Disney Pictures | false | false |
| 2 | 2 | Avatar | $7,227 | -26.3% | 14 | - | $516 | $1,302,281 | 16 | 20th Century Fox International | false | false |
| 3 | - | Besa | $5,619 | - | 5 | - | $1,123 | $6,205 | 1 | N/A | true | false |
| 4 | 3 | Shutter Island | $5,257 | -34.8% | 4 | - | $1,314 | $105,221 | 4 | United International Pictures | false | false |
| 5 | - | Legion | $5,065 | - | 5 | - | $1,013 | $5,065 | 1 | Sony Pictures Releasing | true | false |
| 6 | 6 | The Rebound | $4,244 | -35.5% | 5 | - | $848 | $14,289 | 2 | N/A | false | false |
| 7 | 5 | The Book of Eli | $4,063 | -42.2% | 6 | - | $677 | $30,136 | 3 | Sony Pictures Releasing | false | false |
| 8 | 4 | Edge of Darkness | $3,505 | -52.4% | 5 | - | $701 | $16,599 | 2 | N/A | false | false |
| 9 | - | Toy Story 2 2009 Re-release | $1,552 | - | 3 | - | $517 | $1,703 | 1 | Walt Disney Pictures | true | false |
| 10 | 9 | Percy Jackson & the Olympians: The Lightning Thief | $1,016 | -34.7% | 7 | - | $145 | $40,471 | 6 | 20th Century Fox International | false | false |
| 11 | 7 | The Men Who Stare at Goats | $986 | -59.2% | 4 | - | $246 | $24,751 | 4 | N/A | false | false |
| 12 | 11 | Valentine's Day | $856 | -42.8% | 6 | - | $142 | $129,824 | 8 | Warner Bros. | false | false |
| 13 | 12 | The Princess and the Frog | $803 | -37.8% | 6 | - | $133 | $69,787 | 10 | Walt Disney Pictures | false | false |
| 14 | 15 | Alvin and the Chipmunks: The Squeakquel | $759 | +12.8% | 6 | - | $126 | $60,642 | 12 | 20th Century Fox International | false | false |
| 15 | 16 | Arthur and the Revenge of Maltazard | $593 | -1% | 6 | - | $98 | $63,944 | 14 | N/A | false | false |
| 16 | 8 | The Wolfman | $516 | -74.3% | 6 | - | $86 | $89,193 | 6 | United International Pictures | false | false |
| 17 | 17 | Sherlock Holmes | $296 | -38.1% | 6 | - | $49 | $224,709 | 13 | Warner Bros. | false | false |
| 18 | 20 | Nine | $164 | -10.9% | 4 | - | $41 | $31,740 | 9 | N/A | false | false |
| 19 | 26 | Did You Hear About the Morgans? | $164 | +60.8% | 2 | +1 | $82 | $87,864 | 11 | Sony Pictures Releasing | false | false |
| 20 | 13 | A Serious Man | $158 | -78.3% | 1 | - | $158 | $15,431 | 2 | N/A | false | false |
| 21 | 22 | The Lovely Bones | $139 | -19.2% | 5 | - | $27 | $27,711 | 7 | United International Pictures | false | false |
| 22 | 23 | Garfield's Fun Fest | $100 | -27% | 2 | - | $50 | $14,070 | 15 | N/A | false | false |
| 23 | 24 | Baaria | $99 | -18.9% | 1 | - | $99 | $14,759 | 4 | N/A | false | false |
| 24 | 25 | Law Abiding Citizen | $93 | -9.7% | 5 | - | $18 | $21,081 | 7 | N/A | false | false |
| 25 | 21 | Pope Joan | $75 | -58.6% | 2 | - | $37 | $9,324 | 5 | N/A | false | false |
| 26 | 27 | Invictus 2010 Re-release | $72 | +14.3% | 4 | - | $18 | $25,629 | 5 | Warner Bros. | false | false |
| 27 | 29 | Up in the Air | $47 | +1,075% | 5 | - | $9 | $45,754 | 9 | United International Pictures | false | false |
| 28 | 19 | Daybreakers | $44 | -78.4% | 2 | - | $22 | $2,934 | 4 | N/A | false | false |
| 29 | 28 | Don't Look Back | $38 | +171.4% | 2 | - | $19 | $13,155 | 6 | N/A | false | false |
