| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Clash of the Titans | $549,140 | -51.2% | 116 | +33 | $4,733 | $2,358,011 | 2 | Warner Bros. | false | false |
| 2 | 2 | How to Train Your Dragon | $130,611 | -51.4% | 38 | -17 | $3,437 | $1,319,913 | 3 | United International Pictures | false | false |
| 3 | - | When in Rome | $116,689 | - | 31 | - | $3,764 | $148,089 | 1 | Walt Disney Pictures | true | false |
| 4 | - | The Lovely Bones | $33,435 | - | 15 | - | $2,229 | $38,243 | 1 | United International Pictures | true | false |
| 5 | 3 | Alice in Wonderland | $13,884 | -32.5% | 8 | -3 | $1,735 | $2,004,124 | 6 | Walt Disney Pictures | false | false |
| 6 | 9 | Green Zone | $5,216 | +30.8% | 1 | -2 | $5,216 | $804,784 | 5 | United International Pictures | false | false |
| 7 | 5 | Percy Jackson & the Olympians: The Lightning Thief | $4,985 | -39% | 2 | -2 | $2,492 | $1,523,278 | 9 | 20th Century Fox International | false | false |
| 8 | 4 | The Wolfman | $2,325 | -80.4% | 1 | -4 | $2,325 | $1,081,058 | 8 | United International Pictures | false | false |
| 9 | 7 | It's Complicated | $1,457 | -74.9% | 3 | -3 | $485 | $115,818 | 3 | United International Pictures | false | false |
| 10 | 8 | Shutter Island | $1,167 | -78.5% | 1 | -3 | $1,167 | $581,335 | 6 | United International Pictures | false | false |
| 11 | 10 | Avatar | $229 | -76.8% | 1 | - | $229 | $6,051,259 | 17 | 20th Century Fox International | false | false |
| 12 | 11 | Up in the Air | $59 | -38.5% | 1 | - | $59 | $153,408 | 7 | United International Pictures | false | false |
