| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Bounty Hunter | $442,580 | - | 57 | - | $7,764 | $442,580 | 1 | Sony Pictures Releasing | true | false |
| 2 | 1 | How to Train Your Dragon | $359,162 | -0.6% | 95 | +5 | $3,780 | $1,097,719 | 2 | United International Pictures | false | false |
| 3 | 3 | Alice in Wonderland | $178,586 | -12.7% | 80 | +4 | $2,232 | $2,818,246 | 5 | Walt Disney Pictures | false | false |
| 4 | 2 | Tooth Fairy | $165,172 | -26.3% | 64 | - | $2,580 | $1,054,256 | 3 | 20th Century Fox International | false | false |
| 5 | 4 | The Blind Side | $119,335 | -16.5% | 53 | - | $2,251 | $693,014 | 3 | Warner Bros. | false | false |
| 6 | - | Nanny McPhee Returns | $113,397 | - | 42 | - | $2,699 | $113,397 | 1 | United International Pictures | true | false |
| 7 | 5 | It's Complicated | $78,926 | -21.1% | 53 | -7 | $1,489 | $1,335,649 | 6 | United International Pictures | false | false |
| 8 | 6 | Shutter Island | $63,696 | -31.2% | 35 | -9 | $1,819 | $566,443 | 4 | United International Pictures | false | false |
| 9 | 7 | The Hurt Locker | $56,538 | -17.6% | 21 | - | $2,692 | $169,071 | 2 | NuMetro Distribution | false | false |
| 10 | 8 | Armored | $38,511 | -23.3% | 31 | - | $1,242 | $125,849 | 2 | Sony Pictures Releasing | false | false |
| 11 | 9 | The Book of Eli | $30,785 | -33.8% | 28 | -8 | $1,099 | $740,114 | 6 | Sony Pictures Releasing | false | false |
| 12 | 14 | Avatar | $28,769 | +51.7% | 8 | -3 | $3,596 | $7,772,019 | 16 | 20th Century Fox International | false | false |
| 13 | 10 | Valentine's Day | $21,557 | -33.9% | 31 | -6 | $695 | $1,556,647 | 8 | NuMetro Distribution | false | false |
| 14 | - | Fast & Frantic | $18,959 | - | 25 | - | $758 | $18,959 | 1 | NuMetro Distribution | true | false |
| 15 | 16 | The Last Station 2010 Re-release | $17,064 | -0.7% | 10 | - | $1,706 | $46,930 | 2 | Ster-Kinekor Pictures | false | false |
| 16 | 17 | The Spy Next Door 2010 Re-release | $15,078 | +3.2% | 17 | -1 | $886 | $634,115 | 9 | N/A | false | false |
| 17 | 13 | Nine | $12,287 | -37.3% | 8 | -11 | $1,535 | $168,087 | 4 | Sony Pictures Releasing | false | false |
| 18 | 11 | Remember Me | $12,189 | -59% | 19 | -8 | $641 | $234,504 | 4 | NuMetro Distribution | false | false |
| 19 | 12 | Saw VI | $9,784 | -52.8% | 12 | -8 | $815 | $81,182 | 3 | N/A | false | false |
| 20 | - | The Cove | $5,543 | - | 9 | - | $615 | $5,543 | 1 | N/A | true | false |
| 21 | 20 | An Education | $4,327 | +0.4% | 5 | - | $865 | $181,619 | 10 | United International Pictures | false | false |
| 22 | 19 | Up in the Air | $3,896 | -31% | 6 | -3 | $649 | $450,116 | 10 | United International Pictures | false | false |
| 23 | 23 | Jozi | $433 | -80.7% | 2 | -4 | $216 | $110,104 | 6 | United International Pictures | false | false |
| 24 | - | The Tournament | $430 | - | 1 | - | $430 | $814 | 2 | N/A | false | false |
