| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Book of Eli | $298,017 | - | 20 | - | $14,900 | $323,909 | 1 | Sony Pictures Releasing | true | false |
| 2 | 1 | Clash of the Titans | $255,556 | -53.5% | 83 | -33 | $3,078 | $2,839,771 | 3 | Warner Bros. | false | false |
| 3 | 2 | How to Train Your Dragon | $66,030 | -49.4% | 29 | -9 | $2,276 | $1,426,544 | 4 | United International Pictures | false | false |
| 4 | 3 | When in Rome | $60,576 | -48.1% | 25 | -6 | $2,423 | $252,688 | 2 | Walt Disney Pictures | false | false |
| 5 | 6 | Green Zone | $33,427 | +540.9% | 24 | +23 | $1,392 | $853,104 | 6 | United International Pictures | false | false |
| 6 | - | Date Night | $15,998 | - | 25 | - | $639 | $15,998 | - | 20th Century Fox International | - | false |
| 7 | 4 | The Lovely Bones | $11,658 | -65.1% | 13 | -2 | $896 | $61,339 | 2 | United International Pictures | false | false |
| 8 | - | Cop Out | $9,599 | - | 20 | - | $479 | $9,599 | - | Warner Bros. | - | false |
| 9 | 5 | Alice in Wonderland | $5,611 | -59.6% | 2 | -6 | $2,805 | $2,015,433 | 7 | Walt Disney Pictures | false | false |
| 10 | 7 | Percy Jackson & the Olympians: The Lightning Thief | $5,286 | +6% | 2 | - | $2,643 | $1,533,009 | 10 | 20th Century Fox International | false | false |
| 11 | 10 | Shutter Island | $3,963 | +239.6% | 1 | - | $3,963 | $585,390 | 7 | United International Pictures | false | false |
| 12 | 8 | The Wolfman | $1,641 | -29.4% | 2 | +1 | $820 | $1,083,448 | 9 | United International Pictures | false | false |
| 13 | 11 | Avatar | $624 | +172.5% | 1 | - | $624 | $6,052,399 | 18 | 20th Century Fox International | false | false |
| 14 | 12 | Up in the Air | $546 | +825.4% | 3 | +2 | $182 | $154,220 | 8 | United International Pictures | false | false |
