| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Clash of the Titans | $4,286,144 | - | 533 | - | $8,041 | $4,286,144 | 1 | Warner Bros. | true | false |
| 2 | 1 | The Ghost Writer | $1,012,858 | -26.7% | 352 | +1 | $2,877 | $2,955,622 | 2 | 01 Distribution | false | false |
| 3 | 2 | Green Zone | $754,270 | -44.4% | 295 | -6 | $2,556 | $2,660,159 | 2 | Medusa Distribuzione | false | false |
| 4 | 6 | Basilicata Coast to Coast | $710,347 | +0.3% | 196 | - | $3,624 | $1,788,899 | 2 | Eagle Pictures | false | false |
| 5 | - | From Paris with Love | $579,407 | - | 250 | - | $2,317 | $579,838 | 1 | N/A | true | false |
| 6 | 5 | The Bounty Hunter | $544,648 | -33.8% | 233 | -23 | $2,337 | $1,660,776 | 2 | Sony Pictures Releasing | false | false |
| 7 | 4 | How to Train Your Dragon | $532,679 | -44% | 236 | -116 | $2,257 | $7,054,223 | 4 | Universal Pictures International (UPI) | false | false |
| 8 | 3 | Life Is a Wonderful Thing | $525,098 | -53.9% | 220 | -190 | $2,386 | $5,742,741 | 3 | Medusa Distribuzione | false | false |
| 9 | 7 | Happy Family | $356,488 | -48% | 156 | -140 | $2,285 | $5,744,756 | 4 | 01 Distribution | false | false |
| 10 | - | Cell 211 | $320,473 | - | 173 | - | $1,852 | $320,568 | 1 | N/A | true | false |
| 11 | 10 | Loose Cannons | $212,846 | -42.6% | 78 | -62 | $2,728 | $10,589,588 | 6 | 01 Distribution | false | false |
| 12 | 9 | I Love You Phillip Morris | $174,766 | -61.8% | 111 | -111 | $1,574 | $2,657,224 | 3 | Lucky Red | false | false |
| 13 | - | Fantastic Mr. Fox | $173,950 | - | 98 | - | $1,775 | $173,950 | 1 | 20th Century Fox International | true | false |
| 14 | 8 | Alice in Wonderland | $145,538 | -71% | 90 | -127 | $1,617 | $40,745,546 | 7 | Walt Disney Pictures | false | false |
| 15 | 16 | Departures | $112,365 | +12.1% | - | - | - | $272,747 | 2 | N/A | false | false |
| 16 | 12 | It's Complicated | $78,621 | -57.1% | - | - | - | $5,017,543 | 5 | United International Pictures | false | false |
| 17 | - | No One Knows About Persian Cats | $69,332 | - | - | - | - | $69,332 | 1 | BIM Distribuzione | true | false |
| 18 | 18 | The Concert | $64,673 | -13.2% | - | - | - | $4,532,749 | 11 | BIM Distribuzione | false | false |
| 19 | 13 | Shutter Island | $60,457 | -60.5% | - | - | - | $9,483,572 | 7 | Medusa Distribuzione | false | false |
| 20 | 14 | Little Nicholas | $56,382 | -62.1% | - | - | - | $840,083 | 3 | BIM Distribuzione | false | false |
