| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Iron Man 2 | $2,073,896 | -55.9% | 570 | -11 | $3,638 | $8,056,867 | 2 | Paramount Pictures International | false | false |
| 2 | 2 | OceanWorld | $820,255 | -32.1% | 266 | +29 | $3,083 | $2,344,125 | 2 | Eagle Pictures | false | false |
| 3 | - | Date Night | $752,669 | - | 222 | - | $3,390 | $752,669 | 1 | 20th Century Fox International | true | false |
| 4 | 3 | Weddings and Other Disasters | $616,580 | -41.8% | 276 | -29 | $2,233 | $3,921,146 | 3 | 01 Distribution | false | false |
| 5 | 5 | Come Undone | $555,999 | -33.9% | 284 | +4 | $1,957 | $1,717,070 | 2 | Warner Bros. | false | false |
| 6 | - | Furry Vengeance | $515,113 | - | 226 | - | $2,279 | $515,113 | 1 | Eagle Pictures | true | false |
| 7 | - | Dear John | $441,797 | - | 204 | - | $2,165 | $441,797 | 1 | Sony Pictures Releasing | true | false |
| 8 | 4 | Clash of the Titans | $371,674 | -58.8% | 147 | -156 | $2,528 | $9,567,446 | 4 | Warner Bros. | false | false |
| 9 | 6 | The Last Song | $351,573 | -52.5% | 227 | -20 | $1,548 | $1,275,621 | 2 | Walt Disney Pictures | false | false |
| 10 | - | Draquila - L'Italia che trema | $336,568 | - | - | - | - | $336,568 | 1 | BIM Distribuzione | true | false |
| 11 | 7 | Basilicata Coast to Coast | $191,125 | -39.8% | 89 | -66 | $2,147 | $3,271,976 | 5 | Eagle Pictures | false | false |
| 12 | 9 | The Ghost Writer | $142,914 | -43.7% | 53 | -53 | $2,696 | $4,261,479 | 5 | 01 Distribution | false | false |
| 13 | - | Le ultime 56 ore | $125,395 | - | 184 | - | $681 | $125,395 | 1 | Medusa Distribuzione | true | false |
| 14 | 8 | The Crazies | $91,789 | -70.5% | 58 | -129 | $1,582 | $1,398,230 | 3 | Medusa Distribuzione | false | false |
| 15 | 13 | Wild Grass | $83,762 | -16.9% | 41 | +10 | $2,042 | $220,008 | 2 | BIM Distribuzione | false | false |
| 16 | - | Cirque du Freak: The Vampire's Assistant | $50,728 | - | 96 | - | $528 | $50,728 | 1 | United International Pictures | true | false |
| 17 | 17 | Loose Cannons | $43,106 | -31.6% | - | - | - | $10,370,815 | 9 | 01 Distribution | false | false |
| 18 | 10 | How to Train Your Dragon | $39,648 | -63.8% | - | - | - | $7,244,823 | 7 | Universal Pictures International (UPI) | false | false |
| 19 | 18 | Departures | $34,656 | -42.5% | - | - | - | $557,640 | 5 | N/A | false | false |
| 20 | - | The First Beautiful Thing | $30,978 | - | 18 | - | $1,721 | $8,596,371 | 17 | Medusa Distribuzione | false | false |
| 21 | - | Christine Cristina | $28,009 | - | 20 | - | $1,400 | $28,009 | 1 | 01 Distribution | true | false |
