| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | A Nightmare on Elm Street | $270,756 | - | 53 | - | $5,108 | $270,756 | 1 | Warner Bros. | true | false |
| 2 | 1 | Iron Man 2 | $215,376 | -8.8% | 70 | -25 | $3,076 | $1,299,634 | 3 | United International Pictures | false | false |
| 3 | - | Nanny McPhee Returns | $114,037 | - | 34 | - | $3,354 | $114,037 | 1 | United International Pictures | true | false |
| 4 | 3 | Legion | $113,805 | +12.7% | 40 | -1 | $2,845 | $296,772 | 2 | Sony Pictures Releasing | false | false |
| 5 | 2 | Clash of the Titans | $109,603 | -36.6% | 51 | -31 | $2,149 | $2,678,157 | 5 | Warner Bros. | false | false |
| 6 | - | Toy Story 2009 Re-release | $77,335 | - | 5 | - | $15,467 | $77,335 | 1 | Walt Disney Pictures | true | false |
| 7 | 4 | Date Night | $57,617 | -13% | 28 | -14 | $2,057 | $1,150,798 | 6 | 20th Century Fox International | false | false |
| 8 | - | SubHysteria | $26,806 | - | 15 | - | $1,787 | $26,806 | 1 | N/A | true | false |
| 9 | 6 | Bad Lieutenant: Port of Call New Orleans | $23,266 | -24.7% | 19 | -4 | $1,224 | $90,479 | 2 | N/A | false | false |
| 10 | 7 | How to Train Your Dragon | $18,272 | -19.2% | 33 | -12 | $553 | $1,675,577 | 8 | United International Pictures | false | false |
| 11 | 5 | Paranormal Activity | $14,769 | -52.9% | 9 | -24 | $1,641 | $323,156 | 4 | N/A | false | false |
| 12 | 8 | Dear John | $8,941 | -26.6% | 12 | -3 | $745 | $118,271 | 4 | Sony Pictures Releasing | false | false |
| 13 | 9 | Alice in Wonderland | $7,337 | -29.6% | 14 | -11 | $524 | $4,318,264 | 11 | Walt Disney Pictures | false | false |
| 14 | 10 | I Hate Valentine's Day | $6,250 | -26% | 3 | -7 | $2,083 | $121,563 | 5 | N/A | false | false |
| 15 | 15 | Everybody's Fine | $5,683 | +9.2% | 3 | -7 | $1,894 | $107,071 | 6 | Walt Disney Pictures | false | false |
| 16 | 13 | A Prophet | $4,964 | -12.1% | 2 | -1 | $2,482 | $34,246 | 3 | Sony Pictures Releasing | false | false |
| 17 | 14 | The Imaginarium of Doctor Parnassus | $4,723 | -10.2% | 6 | - | $787 | $99,680 | 5 | Sony Pictures Releasing | false | false |
| 18 | 12 | Case 39 | $3,760 | -44.4% | 5 | -8 | $752 | $263,515 | 6 | United International Pictures | false | false |
| 19 | 17 | The Bounty Hunter | $2,481 | -33.3% | 6 | -2 | $413 | $668,562 | 7 | Sony Pictures Releasing | false | false |
| 20 | 19 | Street Fighter: The Legend of Chun-Li | $1,840 | +23.2% | 3 | -2 | $613 | $36,826 | 4 | N/A | false | false |
| 21 | 21 | The Return 2010 Re-release | $1,612 | +37% | 2 | +1 | $806 | $124,703 | 12 | N/A | false | false |
| 22 | - | Tarata | $1,140 | - | 3 | - | $380 | $1,140 | 1 | N/A | true | false |
| 23 | 22 | The Haunting in Connecticut | $1,010 | -10.9% | 1 | -2 | $1,010 | $270,430 | 8 | N/A | false | false |
| 24 | 18 | 500 Days of Summer | $614 | -61.4% | 1 | -4 | $614 | $94,953 | 8 | 20th Century Fox International | false | false |
| 25 | 11 | Did You Hear About the Morgans? | $442 | -94.3% | 2 | -9 | $221 | $253,991 | 5 | Sony Pictures Releasing | false | false |
| 26 | 20 | Feast 2010 Re-release | $311 | -73.6% | 2 | -1 | $155 | $30,281 | 9 | N/A | false | false |
| 27 | 23 | Couples Retreat | $270 | -64% | 1 | -1 | $270 | $370,826 | 8 | United International Pictures | false | false |
