| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 2 | Prince of Persia: The Sands of Time | $303,160 | -26.2% | 81 | -4 | $3,742 | $815,284 | 2 | Walt Disney Pictures | false | false |
| 2 | 1 | Alice in Wonderland | $279,706 | -34% | 89 | -5 | $3,142 | $2,892,264 | 4 | Walt Disney Pictures | false | false |
| 3 | - | Sex and the City 2 | $241,247 | - | 56 | - | $4,307 | $248,217 | 1 | Warner Bros. | true | false |
| 4 | - | Marmaduke | $145,600 | - | 50 | - | $2,912 | $145,600 | 1 | 20th Century Fox International | true | false |
| 5 | 3 | A Nightmare on Elm Street | $129,451 | -32.8% | 40 | -1 | $3,236 | $787,722 | 3 | Warner Bros. | false | false |
| 6 | - | Case 39 | $46,727 | - | 32 | - | $1,460 | $46,727 | 1 | United International Pictures | true | false |
| 7 | 4 | Iron Man 2 | $17,485 | -63.4% | 15 | -23 | $1,165 | $1,447,123 | 6 | United International Pictures | false | false |
| 8 | 5 | La Esmeralda 1879 | $11,782 | -63.2% | 14 | -17 | $841 | $173,416 | 3 | N/A | false | false |
| 9 | 6 | Ojos Rojos | $9,027 | -71.3% | 11 | -17 | $820 | $582,072 | 5 | N/A | false | false |
| 10 | 9 | The Girl with the Dragon Tattoo | $8,885 | -10.1% | 2 | - | $4,442 | $135,909 | 7 | Andes Films | false | false |
| 11 | 8 | How to Train Your Dragon | $7,121 | -36% | 15 | -3 | $474 | $1,507,651 | 11 | United International Pictures | false | false |
| 12 | 13 | Date Night | $3,765 | -26.7% | 1 | -4 | $3,765 | $124,947 | 5 | 20th Century Fox International | false | false |
| 13 | 7 | Bad Lieutenant: Port of Call New Orleans | $3,349 | -73.7% | 2 | -8 | $1,674 | $60,802 | 3 | N/A | false | false |
| 14 | 12 | Shutter Island | $3,306 | -37.4% | 1 | -3 | $3,306 | $739,576 | 9 | United International Pictures | false | false |
| 15 | 10 | The Book of Eli | $3,132 | -66.5% | 2 | -7 | $1,566 | $252,657 | 5 | Sony Pictures Releasing | false | false |
| 16 | 11 | Clash of the Titans | $2,224 | -70.4% | 5 | -3 | $444 | $1,828,161 | 8 | Warner Bros. | false | false |
| 17 | 14 | The Bounty Hunter | $962 | -19.9% | 2 | -2 | $481 | $113,902 | 7 | Sony Pictures Releasing | false | false |
