| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Toy Story 3 | $1,061,899 | - | 107 | - | $9,924 | $1,061,899 | 1 | Walt Disney Pictures | true | false |
| 2 | 1 | Schuks Tshabalala's Survival Guide to South Africa | $365,948 | -4.1% | 102 | +2 | $3,587 | $3,307,441 | 5 | N/A | false | false |
| 3 | 2 | Death at a Funeral | $122,800 | -2.8% | 45 | - | $2,728 | $332,083 | 2 | Sony Pictures Releasing | false | false |
| 4 | 3 | Marmaduke | $100,968 | -14.7% | 56 | - | $1,803 | $673,217 | 3 | 20th Century Fox International | false | false |
| 5 | - | She's Out of My League | $98,034 | - | 42 | - | $2,334 | $98,034 | 1 | United International Pictures | true | false |
| 6 | 5 | Killers | $80,635 | -7.9% | 49 | -1 | $1,645 | $686,004 | 4 | NuMetro Distribution | false | false |
| 7 | 4 | Prince of Persia: The Sands of Time | $74,317 | -18% | 57 | -16 | $1,303 | $1,473,901 | 6 | Walt Disney Pictures | false | false |
| 8 | 6 | Letters to Juliet | $38,308 | -29.8% | 33 | -9 | $1,160 | $303,019 | 3 | NuMetro Distribution | false | false |
| 9 | 7 | Sex and the City 2 | $28,346 | -39% | 23 | -20 | $1,232 | $918,912 | 5 | 20th Century Fox International | false | false |
| 10 | 9 | Robin Hood | $25,001 | -25.8% | 38 | - | $657 | $967,958 | 7 | United International Pictures | false | false |
| 11 | - | The Fourth Kind | $24,754 | - | 20 | - | $1,237 | $24,754 | 1 | NuMetro Distribution | true | false |
| 12 | 12 | Iron Man 2 | $21,247 | +40.6% | 27 | +4 | $786 | $2,297,405 | 9 | Paramount Pictures International | false | false |
| 13 | 11 | The Last Song | $11,506 | -29.7% | 12 | -8 | $958 | $357,186 | 7 | Walt Disney Pictures | false | false |
| 14 | 10 | Raavan | $10,531 | -49.3% | 13 | - | $810 | $38,851 | 2 | N/A | false | false |
| 15 | 14 | The Back-up Plan | $10,361 | -18.6% | 12 | -5 | $863 | $698,161 | 8 | Sony Pictures Releasing | false | false |
| 16 | 15 | Broken Embraces | $9,691 | -11.5% | 5 | - | $1,938 | $26,495 | 2 | Ster-Kinekor Pictures | false | false |
| 17 | - | Creation | $9,189 | - | 7 | - | $1,312 | $9,189 | 1 | Ster-Kinekor Pictures | true | false |
| 18 | 8 | Egoli: Afrikaners is Plesierig | $7,999 | -77.3% | 46 | - | $173 | $53,736 | 2 | N/A | false | false |
| 19 | 16 | Youth in Revolt | $5,538 | -46.5% | 16 | - | $346 | $25,872 | 2 | Ster-Kinekor Pictures | false | false |
| 20 | 17 | The Imaginarium of Doctor Parnassus | $4,863 | -48.7% | 6 | -4 | $810 | $41,139 | 3 | NuMetro Distribution | false | false |
| 21 | 13 | Green Zone 2010 Re-release | $3,282 | -77.9% | 24 | - | $136 | $251,903 | 5 | United International Pictures | false | false |
| 22 | 20 | Endgame | $1,776 | -47.3% | 5 | - | $355 | $12,045 | 3 | United International Pictures | false | false |
| 23 | 22 | District 13: Ultimatum | $1,346 | -0.7% | 10 | - | $134 | $10,286 | 3 | N/A | false | false |
