| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Twilight Saga: Eclipse | $1,533,542 | - | 88 | - | $17,426 | $1,533,542 | 1 | NuMetro Distribution | true | false |
| 2 | 1 | Toy Story 3 | $384,335 | -63.8% | 107 | - | $3,591 | $1,865,611 | 2 | Walt Disney Pictures | false | false |
| 3 | 2 | Schuks Tshabalala's Survival Guide to South Africa | $294,941 | -19.4% | 97 | -5 | $3,040 | $3,834,570 | 6 | N/A | false | false |
| 4 | 3 | Death at a Funeral | $100,507 | -18.2% | 44 | -1 | $2,284 | $520,172 | 3 | Sony Pictures Releasing | false | false |
| 5 | 4 | Marmaduke | $82,641 | -18.2% | 56 | - | $1,475 | $846,923 | 4 | 20th Century Fox International | false | false |
| 6 | 5 | She's Out of My League | $72,816 | -25.7% | 42 | - | $1,733 | $253,925 | 2 | United International Pictures | false | false |
| 7 | 6 | Killers | $61,578 | -23.6% | 49 | - | $1,256 | $796,808 | 5 | NuMetro Distribution | false | false |
| 8 | 7 | Prince of Persia: The Sands of Time | $48,813 | -34.3% | 45 | -12 | $1,084 | $1,555,194 | 7 | Walt Disney Pictures | false | false |
| 9 | 8 | Letters to Juliet | $25,522 | -33.4% | 30 | -3 | $850 | $358,539 | 4 | NuMetro Distribution | false | false |
| 10 | 10 | Robin Hood | $19,445 | -22.2% | 19 | -19 | $1,023 | $989,718 | 8 | United International Pictures | false | false |
| 11 | 9 | Sex and the City 2 | $16,806 | -40.7% | 17 | -6 | $988 | $943,619 | 6 | 20th Century Fox International | false | false |
| 12 | 11 | The Fourth Kind | $15,012 | -39.4% | 14 | -6 | $1,072 | $60,775 | 2 | NuMetro Distribution | false | false |
| 13 | - | For Better for Worse | $10,423 | - | 9 | - | $1,158 | $10,423 | 1 | N/A | true | false |
| 14 | 15 | The Back-up Plan | $7,687 | -25.8% | 10 | -2 | $768 | $703,667 | 9 | Sony Pictures Releasing | false | false |
| 15 | 17 | Creation | $7,160 | -22.1% | 7 | - | $1,022 | $23,423 | 2 | Ster-Kinekor Pictures | false | false |
| 16 | 13 | The Last Song | $5,992 | -47.9% | 6 | -6 | $998 | $368,226 | 8 | Walt Disney Pictures | false | false |
| 17 | 16 | Broken Embraces | $5,648 | -41.7% | 5 | - | $1,129 | $37,207 | 3 | Ster-Kinekor Pictures | false | false |
| 18 | 12 | Iron Man 2 | $3,957 | -81.4% | 18 | -9 | $219 | $2,281,517 | 10 | Paramount Pictures International | false | false |
| 19 | 20 | The Imaginarium of Doctor Parnassus | $3,823 | -21.4% | 6 | - | $637 | $49,708 | 4 | NuMetro Distribution | false | false |
| 20 | - | Love Happens | $3,350 | - | 9 | - | $372 | $205,367 | 10 | Ster-Kinekor Pictures | false | false |
| 21 | 21 | Green Zone 2010 Re-release | $3,251 | -0.9% | 10 | -14 | $325 | $254,785 | 6 | United International Pictures | false | false |
| 22 | - | Alvin and the Chipmunks: The Squeakquel | $2,532 | - | 13 | - | $194 | $1,764,028 | 28 | N/A | false | false |
| 23 | 22 | Endgame | $601 | -66.2% | 5 | - | $120 | $14,390 | 4 | United International Pictures | false | false |
