| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Inception | $985,154 | - | 57 | - | $17,283 | $985,154 | 1 | Warner Bros. | true | false |
| 2 | 1 | Despicable Me | $732,407 | -15.6% | 47 | - | $15,583 | $1,874,685 | 2 | United International Pictures | false | false |
| 3 | 2 | Predators | $191,370 | -60.6% | 30 | - | $6,379 | $799,953 | 2 | 20th Century Fox International | false | false |
| 4 | 3 | The Twilight Saga: Eclipse | $112,815 | -71.1% | 30 | -21 | $3,760 | $1,938,384 | 3 | Shaw Organisation | false | false |
| 5 | - | A Blood Pledge: Broken Promise 2010 Re-release | $81,704 | - | 5 | - | $16,340 | $121,662 | 1 | Cathay-Keris Films | true | false |
| 6 | - | Hot Tub Time Machine | $58,770 | - | 9 | - | $6,530 | $58,770 | 1 | Cathay-Keris Films | true | false |
| 7 | 4 | Toy Story 3 | $46,831 | -57.9% | 19 | -8 | $2,464 | $3,001,551 | 5 | Walt Disney Pictures | false | false |
| 8 | - | Nodame Cantabile: The Movie II 2010 Re-release | $46,811 | - | 7 | - | $6,687 | $46,811 | 1 | Golden Village Pictures | true | false |
| 9 | 6 | The Legend Is Born: Ip Man | $16,709 | -73.3% | 11 | -7 | $1,519 | $796,714 | 4 | Cathay-Keris Films | false | false |
| 10 | 11 | Chloe | $14,418 | -51.6% | 5 | - | $2,883 | $54,346 | 2 | Shaw Organisation | false | false |
| 11 | - | The Fantastic Water Babes | $11,792 | - | 8 | - | $1,474 | $11,792 | 1 | Golden Village Pictures | true | false |
| 12 | 9 | The Karate Kid | $9,752 | -73.9% | 7 | -9 | $1,393 | $3,345,747 | 6 | Sony Pictures Releasing | false | false |
| 13 | 5 | Knight and Day 2010 Re-release | $7,607 | -90.3% | 10 | -17 | $760 | $1,287,255 | 4 | 20th Century Fox International | false | false |
| 14 | 7 | Triple Tap | $7,405 | -85.3% | 8 | -10 | $925 | $225,979 | 3 | Golden Village Pictures | false | false |
| 15 | 8 | Shanghai | $6,412 | -84.1% | 3 | -7 | $2,137 | $132,573 | 3 | Golden Village Pictures | false | false |
| 16 | 14 | Oceans | $3,837 | -35.8% | 1 | - | $3,837 | $13,989 | 2 | Golden Village Pictures | false | false |
| 17 | 15 | Letters to Juliet | $3,098 | -47.2% | 1 | - | $3,098 | $120,943 | 4 | Shaw Organisation | false | false |
| 18 | 16 | The A-Team | $3,038 | -37.1% | 2 | -2 | $1,519 | $1,135,166 | 6 | 20th Century Fox International | false | false |
| 19 | 12 | Secret Sunday | $1,912 | -92.4% | 1 | -4 | $1,912 | $101,956 | 3 | Cathay-Keris Films | false | false |
| 20 | 17 | Sex and the City 2 | $358 | -82.4% | 1 | - | $358 | $1,219,541 | 8 | Golden Village Pictures | false | false |
