| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Twilight Saga: Eclipse | $470,329 | -69.3% | 88 | - | $5,344 | $2,606,041 | 2 | NuMetro Distribution | false | false |
| 2 | 2 | Toy Story 3 | $328,249 | -14.6% | 107 | - | $3,067 | $2,623,167 | 3 | Walt Disney Pictures | false | false |
| 3 | 3 | Schuks Tshabalala's Survival Guide to South Africa | $254,735 | -13.6% | 94 | -3 | $2,709 | $4,382,147 | 7 | N/A | false | false |
| 4 | 4 | Death at a Funeral | $76,576 | -23.8% | 40 | -4 | $1,914 | $686,034 | 4 | Sony Pictures Releasing | false | false |
| 5 | 5 | Marmaduke | $70,104 | -15.2% | 56 | - | $1,251 | $1,021,523 | 5 | 20th Century Fox International | false | false |
| 6 | 6 | She's Out of My League | $60,126 | -17.4% | 42 | - | $1,431 | $451,754 | 3 | United International Pictures | false | false |
| 7 | 7 | Killers | $50,430 | -18.1% | 43 | -6 | $1,172 | $912,596 | 6 | NuMetro Distribution | false | false |
| 8 | - | I Love You Phillip Morris | $49,400 | - | 43 | - | $1,148 | $49,400 | 1 | United International Pictures | true | false |
| 9 | 8 | Prince of Persia: The Sands of Time | $37,030 | -24.1% | 33 | -12 | $1,122 | $1,664,549 | 8 | Walt Disney Pictures | false | false |
| 10 | - | The Boys Are Back | $18,383 | - | 10 | - | $1,838 | $18,383 | 1 | N/A | true | false |
| 11 | 9 | Letters to Juliet | $17,270 | -32.3% | 20 | -10 | $863 | $410,141 | 5 | NuMetro Distribution | false | false |
| 12 | 10 | Robin Hood | $17,003 | -12.6% | 14 | -5 | $1,214 | $1,058,475 | 9 | United International Pictures | false | false |
| 13 | - | Milenge Milenge | $14,519 | - | 6 | - | $2,419 | $14,519 | 1 | N/A | true | false |
| 14 | - | The Runaways | $10,548 | - | 15 | - | $703 | $10,548 | 1 | NuMetro Distribution | true | false |
| 15 | - | Diary of a Wimpy Kid | $8,935 | - | 10 | - | $893 | $8,935 | 1 | NuMetro Distribution | true | false |
| 16 | 13 | For Better for Worse | $8,596 | -17.5% | 9 | - | $955 | $27,476 | 2 | N/A | false | false |
| 17 | 18 | Iron Man 2 | $8,093 | +104.5% | 15 | -3 | $539 | $2,345,971 | 11 | Paramount Pictures International | false | false |
| 18 | 15 | Creation | $7,093 | -0.9% | 7 | - | $1,013 | $36,281 | 3 | Ster-Kinekor Pictures | false | false |
| 19 | 11 | Sex and the City 2 | $6,379 | -62% | 10 | -7 | $637 | $981,707 | 7 | 20th Century Fox International | false | false |
| 20 | 17 | Broken Embraces | $5,621 | -0.5% | 5 | - | $1,124 | $47,183 | 4 | Ster-Kinekor Pictures | false | false |
| 21 | 14 | The Back-up Plan | $4,353 | -43.4% | 6 | -4 | $725 | $727,320 | 10 | Sony Pictures Releasing | false | false |
| 22 | 16 | The Last Song | $3,625 | -39.5% | 5 | -1 | $725 | $385,001 | 9 | Walt Disney Pictures | false | false |
| 23 | 21 | Green Zone 2010 Re-release | $3,191 | -1.8% | 9 | -1 | $354 | $267,966 | 7 | United International Pictures | false | false |
| 24 | 23 | Endgame | $969 | +61.2% | 2 | -3 | $484 | $16,615 | 5 | United International Pictures | false | false |
