| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Shrek Forever After | $820,956 | - | 105 | - | $7,818 | $820,956 | 1 | United International Pictures | true | false |
| 2 | 1 | The Twilight Saga: Eclipse | $258,019 | -45.1% | 88 | - | $2,932 | $3,047,655 | 3 | NuMetro Distribution | false | false |
| 3 | 3 | Schuks Tshabalala's Survival Guide to South Africa | $152,070 | -40.3% | 92 | -2 | $1,652 | $4,655,579 | 8 | N/A | false | false |
| 4 | 2 | Toy Story 3 | $108,504 | -66.9% | 74 | -33 | $1,466 | $2,854,173 | 4 | Walt Disney Pictures | false | false |
| 5 | 4 | Death at a Funeral | $59,999 | -21.6% | 39 | -1 | $1,538 | $789,100 | 5 | Sony Pictures Releasing | false | false |
| 6 | - | A Nightmare on Elm Street | $56,376 | - | 25 | - | $2,255 | $56,376 | 1 | NuMetro Distribution | true | false |
| 7 | 7 | Killers | $35,117 | -30.4% | 35 | -8 | $1,003 | $975,785 | 7 | NuMetro Distribution | false | false |
| 8 | 6 | She's Out of My League | $31,993 | -46.8% | 27 | -15 | $1,184 | $443,737 | 4 | United International Pictures | false | false |
| 9 | 8 | I Love You Phillip Morris | $31,317 | -36.6% | 43 | - | $728 | $108,288 | 2 | United International Pictures | false | false |
| 10 | 5 | Marmaduke | $18,670 | -73.4% | 49 | -7 | $381 | $1,066,675 | 6 | 20th Century Fox International | false | false |
| 11 | 9 | Prince of Persia: The Sands of Time | $18,485 | -50.1% | 24 | -9 | $770 | $1,702,113 | 9 | Walt Disney Pictures | false | false |
| 12 | 10 | The Boys Are Back | $15,213 | -17.2% | 10 | - | $1,521 | $43,761 | 2 | N/A | false | false |
| 13 | 11 | Letters to Juliet | $11,764 | -31.9% | 14 | -6 | $840 | $432,053 | 6 | NuMetro Distribution | false | false |
| 14 | 12 | Robin Hood | $9,704 | -42.9% | 10 | -4 | $970 | $1,370,251 | 10 | United International Pictures | false | false |
| 15 | 13 | Milenge Milenge | $8,998 | -38% | 6 | - | $1,499 | $28,569 | 2 | N/A | false | false |
| 16 | 14 | The Runaways | $8,351 | -20.8% | 15 | - | $556 | $25,560 | 2 | NuMetro Distribution | false | false |
| 17 | 18 | Creation | $7,495 | +5.7% | 7 | - | $1,070 | $48,177 | 4 | Ster-Kinekor Pictures | false | false |
| 18 | 20 | Broken Embraces | $5,483 | -2.5% | 5 | - | $1,096 | $55,964 | 5 | Ster-Kinekor Pictures | false | false |
| 19 | - | Themba | $4,099 | - | 10 | - | $409 | $4,099 | 1 | N/A | true | false |
| 20 | 15 | Diary of a Wimpy Kid | $3,664 | -59% | 10 | - | $366 | $15,935 | 2 | NuMetro Distribution | false | false |
| 21 | 21 | The Back-up Plan | $3,014 | -30.8% | 6 | - | $502 | $730,445 | 11 | Sony Pictures Releasing | false | false |
| 22 | 23 | Green Zone 2010 Re-release | $2,625 | -17.7% | 11 | +2 | $238 | $272,882 | 8 | United International Pictures | false | false |
| 23 | 17 | Iron Man 2 | $1,978 | -75.6% | 8 | -7 | $247 | $2,351,573 | 12 | Paramount Pictures International | false | false |
