| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Inception | $45,804 | - | 7 | - | $6,543 | $52,793 | 1 | - | true | false |
| 2 | 2 | Toy Story 3 | $14,289 | -20.7% | 13 | - | $1,099 | $114,658 | 3 | Universal Pictures International (UPI) | false | false |
| 3 | 1 | Knight and Day 2010 Re-release | $9,493 | -64.9% | 6 | - | $1,582 | $60,274 | 2 | Universal Pictures International (UPI) | false | false |
| 4 | 3 | The Twilight Saga: Eclipse | $9,289 | -33.9% | 7 | - | $1,327 | $248,622 | 4 | ACME | false | false |
| 5 | 5 | Shrek Forever After | $6,396 | -3.1% | 8 | -3 | $799 | $581,499 | 8 | Universal Pictures International (UPI) | false | false |
| 6 | 4 | StreetDance 2 | $5,324 | -26.9% | 4 | - | $1,331 | $143,294 | 5 | N/A | false | false |
| 7 | - | Turtle: The Incredible Journey | $4,745 | - | 5 | - | $949 | $4,745 | 1 | N/A | true | false |
| 8 | - | Letters to Juliet | $4,447 | - | 4 | - | $1,111 | $6,382 | 1 | ACME | true | false |
| 9 | 6 | Centurion | $3,021 | -48.4% | 4 | +1 | $755 | $27,805 | 3 | ACME | false | false |
| 10 | 9 | The Young Victoria | $1,356 | +26.3% | 2 | -1 | $678 | $39,103 | 6 | N/A | false | false |
| 11 | 7 | Prince of Persia: The Sands of Time | $1,016 | -57% | 8 | - | $127 | $168,911 | 9 | Universal Pictures International (UPI) | false | false |
| 12 | 10 | Sex and the City 2 | $667 | -34.9% | 2 | - | $333 | $207,607 | 9 | - | false | false |
| 13 | 8 | Killers | $623 | -56.3% | 2 | - | $311 | $80,785 | 7 | ACME | false | false |
| 14 | 14 | The A-Team | $424 | +9.6% | 6 | - | $70 | $49,589 | 7 | Universal Pictures International (UPI) | false | false |
| 15 | 17 | Coco Before Chanel | $244 | +134.6% | 1 | -1 | $244 | $81,841 | 21 | N/A | false | false |
| 16 | 23 | Alice in Wonderland | $181 | +761.9% | 3 | - | $60 | $496,181 | 21 | Universal Pictures International (UPI) | false | false |
| 17 | 15 | The Princess and the Frog | $110 | -43% | 3 | - | $36 | $251,250 | 26 | Universal Pictures International (UPI) | false | false |
| 18 | 11 | Dear John | $75 | -90% | 2 | - | $37 | $45,779 | 15 | N/A | false | false |
| 19 | 20 | Small Crime | $75 | +108.3% | 1 | - | $75 | $2,669 | 11 | N/A | false | false |
| 20 | 18 | Up | $73 | -18% | 1 | - | $73 | $392,151 | 49 | Universal Pictures International (UPI) | false | false |
| 21 | - | Alvin and the Chipmunks: The Squeakquel | $61 | - | 1 | - | $61 | $297,960 | 31 | Universal Pictures International (UPI) | false | false |
| 22 | - | Up in the Air | $58 | - | 1 | - | $58 | $61,555 | 27 | Universal Pictures International (UPI) | false | false |
| 23 | 16 | How to Train Your Dragon | $55 | -56% | 2 | +1 | $27 | $330,647 | 17 | Universal Pictures International (UPI) | false | false |
