| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Inception | $621,541 | -14.8% | 85 | -2 | $7,312 | $1,634,773 | 2 | Warner Bros. | false | false |
| 2 | - | Killers | $149,503 | - | 42 | - | $3,559 | $149,503 | 1 | Roadshow Films | true | false |
| 3 | 3 | Toy Story 3 | $143,599 | -23.2% | 93 | -3 | $1,544 | $3,597,530 | 5 | Walt Disney Pictures | false | false |
| 4 | - | The Girl Who Played with Fire | $133,855 | - | 42 | - | $3,187 | $223,111 | 1 | Rialto Distribution | true | false |
| 5 | 2 | Knight and Day 2010 Re-release | $110,748 | -42.6% | 65 | -8 | $1,703 | $947,298 | 3 | 20th Century Fox International | false | false |
| 6 | 4 | The Karate Kid | $83,836 | -42.4% | 50 | -11 | $1,676 | $1,926,433 | 4 | Sony Pictures Releasing | false | false |
| 7 | 5 | The Twilight Saga: Eclipse | $80,497 | -41.8% | 71 | -3 | $1,133 | $3,719,240 | 5 | Hoyts Distribution | false | false |
| 8 | 7 | Shrek Forever After | $57,578 | -30.1% | 79 | -11 | $728 | $3,430,717 | 7 | Paramount Pictures International | false | false |
| 9 | 8 | Predators | $22,769 | -39.3% | 25 | -18 | $910 | $481,363 | 4 | 20th Century Fox International | false | false |
| 10 | 11 | The Last Station 2010 Re-release | $16,332 | -12.4% | 16 | -6 | $1,020 | $744,700 | 9 | Rialto Distribution | false | false |
| 11 | 12 | Aftershock | $15,938 | -0.6% | 3 | - | $5,312 | $46,442 | 2 | N/A | false | false |
| 12 | 10 | Marmaduke | $15,600 | -19.8% | 42 | -5 | $371 | $476,574 | 5 | 20th Century Fox International | false | false |
| 13 | 13 | Cemetery Junction | $11,491 | -26.1% | 9 | -5 | $1,276 | $230,649 | 7 | Sony Pictures Releasing | false | false |
| 14 | - | The Girl with the Dragon Tattoo | $10,390 | - | 14 | - | $742 | $975,346 | 33 | Rialto Distribution | false | false |
| 15 | - | Boy | $7,022 | - | 24 | - | $292 | $6,726,647 | - | Madman Entertainment | - | false |
| 16 | 18 | The Secret in Their Eyes | $6,980 | -24.1% | 12 | - | $581 | $425,737 | 12 | Rialto Distribution | false | false |
| 17 | 14 | Khatta Meetha | $6,937 | -49.4% | 5 | +1 | $1,387 | $26,980 | 2 | - | false | false |
| 18 | 16 | The A-Team | $5,583 | -49.9% | 19 | -2 | $293 | $1,531,578 | 8 | 20th Century Fox International | false | false |
| 19 | 21 | Welcome | $4,805 | -23.8% | 5 | - | $961 | $49,569 | 5 | Palace Films | false | false |
| 20 | 20 | My One and Only | $4,149 | -39.6% | 12 | -1 | $345 | $53,406 | 4 | Madman Entertainment | false | false |
| 21 | 17 | Get Him to the Greek | $4,093 | -62% | 9 | -8 | $454 | $709,112 | 7 | United International Pictures | false | false |
| 22 | 19 | Me and Orson Welles | $3,062 | -57.1% | 16 | -9 | $191 | $86,879 | 5 | Madman Entertainment | false | false |
| 23 | 22 | The Blind Side | $3,061 | -27.3% | 14 | -2 | $218 | $1,276,294 | 13 | Warner Bros. | false | false |
| 24 | 24 | A Single Man | $1,661 | -54.1% | 10 | -2 | $166 | $462,252 | 13 | Icon Film Distribution | false | false |
| 25 | 23 | Sex and the City 2 | $1,540 | -61.5% | 13 | -13 | $118 | $1,736,359 | 9 | Roadshow Films | false | false |
| 26 | - | Home by Christmas | $1,157 | - | 4 | - | $289 | $827,274 | 15 | - | false | false |
| 27 | 28 | Letters to Juliet | $1,133 | +97% | 5 | - | $226 | $346,859 | 12 | Hoyts Distribution | false | false |
| 28 | 27 | With or Without You | $725 | -16.3% | 3 | - | $241 | $68,844 | 24 | - | false | false |
| 29 | 26 | The Hedgehog | $482 | -46% | 4 | -1 | $120 | $93,324 | 14 | Madman Entertainment | false | false |
| 30 | 25 | Coco Chanel & Igor Stravinsky | $397 | -64.4% | 7 | -3 | $56 | $115,426 | 9 | Madman Entertainment | false | false |
| 31 | 30 | I Hate Luv Storys | $219 | -57.2% | 1 | - | $219 | $23,813 | 5 | Mind Blowing Films | false | false |
| 32 | 31 | Micmacs | $201 | -56.7% | 2 | -3 | $100 | $59,305 | 8 | Hopscotch Films | false | false |
| 33 | 33 | The Way 2010 Re-release | $73 | -64.4% | 1 | - | $73 | $5,425 | 11 | Madman Entertainment | false | false |
