| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Inception | $28,889 | -36.9% | 7 | - | $4,127 | $136,658 | 2 | - | false | false |
| 2 | - | Predators | $21,182 | - | 6 | - | $3,530 | $22,179 | 1 | Universal Pictures International (UPI) | true | false |
| 3 | - | Grown Ups | $10,451 | - | 5 | - | $2,090 | $11,434 | 1 | Sony Pictures Releasing | true | false |
| 4 | 2 | Toy Story 3 | $10,370 | -27.4% | 13 | - | $797 | $145,937 | 4 | Universal Pictures International (UPI) | false | false |
| 5 | 3 | Knight and Day 2010 Re-release | $7,163 | -24.5% | 7 | +1 | $1,023 | $86,798 | 3 | Universal Pictures International (UPI) | false | false |
| 6 | 6 | StreetDance 2 | $6,513 | +22.3% | 4 | - | $1,628 | $161,260 | 6 | N/A | false | false |
| 7 | 4 | The Twilight Saga: Eclipse | $5,904 | -36.4% | 7 | - | $843 | $269,191 | 5 | ACME | false | false |
| 8 | 7 | Turtle: The Incredible Journey | $4,026 | -15.2% | 5 | - | $805 | $17,988 | 2 | N/A | false | false |
| 9 | 8 | Letters to Juliet | $3,918 | -11.9% | 4 | - | $979 | $17,880 | 2 | ACME | false | false |
| 10 | 5 | Shrek Forever After | $3,440 | -46.2% | 7 | -1 | $491 | $592,390 | 9 | Universal Pictures International (UPI) | false | false |
| 11 | 9 | Centurion | $1,369 | -54.7% | 4 | - | $342 | $32,383 | 4 | ACME | false | false |
| 12 | 16 | Alice in Wonderland | $853 | +371.3% | 2 | -1 | $426 | $495,907 | 22 | Universal Pictures International (UPI) | false | false |
| 13 | 19 | Small Crime | $388 | +417.3% | 1 | - | $388 | $3,137 | 12 | N/A | false | false |
| 14 | 10 | The Young Victoria | $337 | -75.1% | 2 | - | $168 | $40,105 | 7 | N/A | false | false |
| 15 | 12 | Sex and the City 2 | $262 | -60.7% | 2 | - | $131 | $208,881 | 10 | - | false | false |
| 16 | 23 | How to Train Your Dragon | $187 | +240% | 2 | - | $93 | $330,946 | 18 | Universal Pictures International (UPI) | false | false |
| 17 | 14 | The A-Team | $157 | -63% | 2 | -4 | $78 | $50,147 | 8 | Universal Pictures International (UPI) | false | false |
| 18 | 11 | Prince of Persia: The Sands of Time | $123 | -87.9% | 2 | -6 | $61 | $170,693 | 10 | Universal Pictures International (UPI) | false | false |
| 19 | 15 | Coco Before Chanel | $86 | -64.8% | 1 | - | $86 | $82,305 | 22 | N/A | false | false |
| 20 | - | Dorian Gray | $55 | - | 1 | - | $55 | $33,799 | 14 | N/A | false | false |
| 21 | 21 | Alvin and the Chipmunks: The Squeakquel | $45 | -26.2% | 2 | +1 | $22 | $297,941 | 32 | Universal Pictures International (UPI) | false | false |
| 22 | 20 | Up | $20 | -72.6% | 1 | - | $20 | $391,963 | 50 | Universal Pictures International (UPI) | false | false |
| 23 | - | Nanny McPhee Returns | $17 | - | 1 | - | $17 | $23,713 | 14 | Universal Pictures International (UPI) | false | false |
| 24 | - | Avatar | $14 | - | 1 | - | $14 | $1,391,066 | 33 | 20th Century Fox International | false | false |
| 25 | - | Bad Lieutenant: Port of Call New Orleans | $9 | - | 1 | - | $9 | $27,782 | 24 | N/A | false | false |
