| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Expendables | $510,002 | -19.2% | 52 | - | $9,807 | $1,335,273 | 2 | Benelux Film Distributors | false | false |
| 2 | 2 | Step Up 3D | $365,737 | +8.8% | 61 | -4 | $5,995 | $2,469,899 | 4 | Belga Films | false | false |
| 3 | 3 | Inception | $313,730 | +10.4% | 92 | - | $3,410 | $4,424,002 | 6 | Warner Bros. | false | false |
| 4 | 5 | Marmaduke | $279,131 | +40.5% | 48 | - | $5,815 | $570,224 | 2 | 20th Century Fox International | false | false |
| 5 | 4 | The Sorcerer's Apprentice | $260,588 | +3.7% | 57 | - | $4,571 | $1,244,500 | 3 | Walt Disney Pictures | false | false |
| 6 | 6 | A Turtle's Tale: Sammy's Adventures | $245,206 | +36% | 62 | - | $3,954 | $1,307,941 | 4 | Kinepolis Film Distribution (KFD) | false | false |
| 7 | - | The Switch | $198,432 | - | 31 | - | $6,401 | $212,117 | 1 | Paradiso Entertainment | true | false |
| 8 | 7 | The Last Airbender | $185,116 | +5.1% | 63 | - | $2,938 | $2,794,147 | 5 | Universal Pictures International (UPI) | false | false |
| 9 | 8 | Salt | $173,097 | +24.1% | 46 | - | $3,762 | $1,310,682 | 4 | Sony Pictures Releasing | false | false |
| 10 | 12 | Toy Story 3 | $162,862 | +50.6% | 72 | -6 | $2,261 | $4,858,996 | 10 | Walt Disney Pictures | false | false |
| 11 | 11 | Shrek Forever After | $143,150 | +32% | 83 | -5 | $1,724 | $4,422,030 | 7 | Universal Pictures International (UPI) | false | false |
| 12 | 10 | Cats & Dogs: The Revenge of Kitty Galore | $139,952 | +21.7% | 67 | -4 | $2,088 | $1,133,725 | 4 | Warner Bros. | false | false |
| 13 | 9 | Knight and Day 2010 Re-release | $121,575 | -4.1% | 72 | -13 | $1,688 | $2,180,890 | 5 | 20th Century Fox International | false | false |
| 14 | - | Letters to Juliet | $119,945 | - | 30 | - | $3,998 | $162,919 | 1 | Belga Films | true | false |
| 15 | 13 | The Karate Kid | $94,246 | +7.6% | 45 | -9 | $2,094 | $2,183,344 | 6 | Sony Pictures Releasing | false | false |
| 16 | 14 | The Twilight Saga: Eclipse | $57,533 | -9.5% | 34 | -14 | $1,692 | $6,367,281 | 9 | Belga Films | false | false |
| 17 | - | The Tree | $55,491 | - | 12 | - | $4,624 | $66,279 | 1 | Cinéart | true | false |
| 18 | 18 | Tinker Bell and the Lost Treasure | $41,217 | +89.5% | 16 | -1 | $2,576 | $76,989 | 2 | Walt Disney Pictures | false | false |
| 19 | 15 | Love Crime | $33,187 | -21.6% | 17 | - | $1,952 | $95,626 | 2 | Benelux Film Distributors | false | false |
| 20 | - | In Gold We Trust | $25,310 | - | 11 | - | $2,300 | $25,391 | 1 | Les Films de l'Elysée | true | false |
| 21 | 17 | The Killer Inside Me | $24,061 | -16.6% | 10 | - | $2,406 | $73,051 | 2 | Paradiso Entertainment | false | false |
| 22 | 19 | Copacabana Palace 2010 Re-release | $17,204 | -19.2% | 11 | - | $1,564 | $120,691 | 3 | Cinéart | false | false |
| 23 | 20 | Killers | $16,396 | -12.4% | 6 | -2 | $2,732 | $1,010,344 | 8 | Kinepolis Film Distribution (KFD) | false | false |
| 24 | 21 | With Love... from the Age of Reason | $13,186 | -25.4% | 13 | - | $1,014 | $173,502 | 4 | Cinéart | false | false |
| 25 | - | Ondine | $11,744 | - | 4 | - | $2,936 | $13,416 | 1 | Kinepolis Film Distribution (KFD) | true | false |
| 26 | 22 | Hot Tub Time Machine | $9,849 | -33.8% | 9 | -6 | $1,094 | $139,160 | 3 | 20th Century Fox International | false | false |
| 27 | 23 | The Italian | $8,391 | +4.1% | 11 | - | $762 | $331,791 | 7 | Alternative Films | false | false |
| 28 | 32 | L'autre monde 2010 Re-release | $4,980 | +136.5% | 7 | -5 | $711 | $21,910 | 2 | N/A | false | false |
| 29 | 16 | Get Him to the Greek | $4,578 | -84.2% | 5 | -9 | $915 | $47,024 | 2 | Universal Pictures International (UPI) | false | false |
| 30 | 27 | Furry Vengeance | $4,565 | +18.1% | 9 | +1 | $507 | $180,994 | 6 | Belga Films | false | false |
| 31 | 25 | Come Undone | $3,817 | -9.8% | 6 | +1 | $636 | $21,209 | 3 | ABC Distribution | false | false |
| 32 | 31 | Law Abiding Citizen | $2,789 | +21.6% | 1 | - | $2,789 | $469,083 | 13 | Belga Films | false | false |
| 33 | 26 | My Afternoons with Margueritte | $2,689 | -36% | 10 | - | $268 | $221,477 | 10 | Cinéart | false | false |
| 34 | 36 | The Last Station 2010 Re-release | $2,463 | +61.3% | 4 | - | $615 | $47,201 | 11 | Belga Films | false | false |
| 35 | 30 | The Fourth Kind | $2,059 | -21.2% | 5 | - | $411 | $93,318 | 5 | Kinepolis Film Distribution (KFD) | false | false |
| 36 | 28 | Babies | $2,020 | -39.8% | 4 | - | $505 | $55,178 | 6 | Cinéart | false | false |
| 37 | 39 | The Ghost Writer | $1,923 | +135.4% | 3 | +1 | $641 | $872,922 | 23 | Benelux Film Distributors | false | false |
| 38 | - | The Blonde with Bare Breasts | $1,812 | - | 6 | - | $302 | $3,492 | 1 | Benelux Film Distributors | true | false |
| 39 | 29 | The Back-up Plan | $1,790 | -39% | 1 | - | $1,790 | $369,138 | 10 | Sony Pictures Releasing | false | false |
| 40 | 37 | The Illusionist | $1,562 | +37.6% | 4 | - | $390 | $55,837 | 11 | Paradiso Entertainment | false | false |
| 41 | 38 | Baaria | $352 | -65.7% | 3 | -1 | $117 | $49,127 | 9 | Paradiso Entertainment | false | false |
| 42 | 40 | Chicas | $328 | +28.1% | 1 | -2 | $328 | $8,655 | 7 | Benelux Film Distributors | false | false |
| 43 | 41 | Splice 2010 Re-release | $175 | -13.4% | 1 | -11 | $175 | $86,434 | 5 | Benelux Film Distributors | false | false |
| 44 | 42 | Agora | $165 | -13.2% | 1 | -1 | $165 | $169,087 | 19 | Benelux Film Distributors | false | false |
| 45 | 43 | Alamar | $67 | -51.1% | 1 | -3 | $67 | $16,770 | 8 | Benelux Film Distributors | false | false |
