| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Inception | $14,974 | -17.4% | 8 | - | $1,871 | $579,513 | 7 | Warner Bros. | false | false |
| 2 | - | Predators | $6,172 | - | 5 | - | $1,234 | $6,172 | 1 | 20th Century Fox International | true | false |
| 3 | 3 | Salt | $5,880 | -26.1% | 8 | - | $735 | $280,957 | 6 | Sony Pictures Releasing | false | false |
| 4 | 2 | Grown Ups | $5,550 | -35.3% | 5 | - | $1,110 | $112,363 | 4 | Sony Pictures Releasing | false | false |
| 5 | 4 | The Last Airbender | $4,213 | +0.6% | 8 | - | $526 | $172,818 | 6 | United International Pictures | false | false |
| 6 | 8 | Toy Story 3 | $3,454 | +10.8% | 2 | - | $1,727 | $410,852 | 11 | Walt Disney Pictures | false | false |
| 7 | 5 | The Twilight Saga: Eclipse | $3,176 | -22.4% | 5 | - | $635 | $437,284 | 8 | - | false | false |
| 8 | 7 | Shrek Forever After | $2,491 | -24% | 8 | - | $311 | $249,841 | 9 | United International Pictures | false | false |
| 9 | 6 | Knight and Day 2010 Re-release | $2,150 | -35% | 3 | -1 | $716 | $409,918 | 9 | 20th Century Fox International | false | false |
| 10 | 9 | The Karate Kid | $1,468 | -11.7% | 1 | - | $1,468 | $177,739 | 10 | Sony Pictures Releasing | false | false |
| 11 | 10 | Prince of Persia: The Sands of Time | $677 | -42.4% | 1 | - | $677 | $345,819 | 14 | Walt Disney Pictures | false | false |
| 12 | 12 | Robin Hood | $583 | +5% | 4 | - | $145 | $379,779 | 16 | United International Pictures | false | false |
| 13 | 11 | She's Out of My League | $408 | -59.7% | 5 | +1 | $81 | $51,393 | 8 | United International Pictures | false | false |
| 14 | - | Iron Man 2 | $24 | - | 1 | - | $24 | $301,169 | 18 | United International Pictures | false | false |
