| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Cats & Dogs: The Revenge of Kitty Galore | $15,544 | - | 5 | - | $3,108 | $15,544 | 1 | Warner Bros. | true | false |
| 2 | - | Vampires Suck | $14,933 | - | 4 | - | $3,733 | $14,933 | 1 | 20th Century Fox International | true | false |
| 3 | 1 | The Expendables | $14,842 | -55.9% | 3 | - | $4,947 | $72,404 | 2 | N/A | false | false |
| 4 | 2 | Grown Ups | $13,341 | -35.2% | 4 | +1 | $3,335 | $54,889 | 2 | Sony Pictures Releasing | false | false |
| 5 | 3 | The Last Airbender | $10,659 | -43.7% | 5 | - | $2,131 | $125,634 | 3 | United International Pictures | false | false |
| 6 | 4 | Inception | $8,087 | -28.5% | 6 | +1 | $1,347 | $243,994 | 6 | Warner Bros. | false | false |
| 7 | 6 | Salt | $4,362 | -22.2% | 5 | - | $872 | $88,530 | 4 | Sony Pictures Releasing | false | false |
| 8 | 5 | Toy Story 3 | $4,353 | -42.1% | 6 | -3 | $725 | $180,643 | 7 | Walt Disney Pictures | false | false |
| 9 | 8 | The Sorcerer's Apprentice | $3,456 | -12.4% | 5 | +2 | $691 | $93,282 | 5 | Walt Disney Pictures | false | false |
| 10 | 7 | Letters to Juliet | $3,329 | -28% | 2 | - | $1,664 | $59,247 | 6 | N/A | false | false |
